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뒤시엔느형 근디스트로피에서 폐 역학 및 기침 관련 인자에 대한 분석

Other Titles
 Analysis of Pulmonary Mechanics and the Factors for Coughing in Duchenne Muscular Dystrophy 
 강성웅  ;  나동욱  ;  문재호  ;  강윤주  ;  강연승  ;  류호현 
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지), Vol.27(1) : 43-48, 2003 
Journal Title
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지) 
Issue Date
Maximum insufflation capacity ; Peak cough flow ; Pulmonary compliance ; Assisted cough
Maximum insufflation capacity ; Peak cough flow ; Pulmonary compliance ; Assisted cough
Objective: To investigate the pathologic pulmonary mechanics and analyze the factors affecting cough ability in patients with Duchenne muscular dystrophy (DMD). Method: Thirty-one patients with DMD were investigated. The vital capacity (VC), maximum insufflation capacity (MIC), maximal inspiratory (MIP), and expiratory pressure (MEP) were measured. Unassisted peak cough flow (UPCF) and assisted PCF at three different conditions were evaluated. Results: The mean value of MICs (1,873⁑644 cc) was higher than that of VCs (1,509⁑640 cc). MIP and MEP were 48.8⁑21.4% and 29.5⁑19.5% of predicted normal value respectively. MIP was correlated with UPCFs as well as MEP. All of three assisted cough methods showed significantly higher value than unassisted method (p<0.01). The manual assisted PCFs at MIC significantly exceeded those produced by manual assisted or PCFs at MIC. The positive correlation between the MIC-VC difference and PCF at MIC-UPCF difference was seen (p<0.01). Conclusion: Inspiratory muscle strength and the preservation of pulmonary compliance is important for the development of effective cough as well as expiratory muscle power. Thus, the clinical implication of the inspiratory phase in assisting a cough should be emphasized.
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1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seong Woong(강성웅) ORCID logo https://orcid.org/0000-0002-7279-3893
Rha, Dong Wook(나동욱) ORCID logo https://orcid.org/0000-0002-7153-4937
Ryu, Ho Hyun(류호현)
Moon, Jae Ho(문재호)
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