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Effects of CETP gene polymorphisms on atherogenic lipoprotein phenotypes in Koreans
DC Field | Value | Language |
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dc.contributor.author | 이종은 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 조은영 | - |
dc.date.accessioned | 2015-07-15T16:37:34Z | - |
dc.date.available | 2015-07-15T16:37:34Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 1229-232X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/113273 | - |
dc.description.abstract | Small dense LDL(LDL III) is emerging as a major risk factor for coronary artery disease. LDL III generation is associated with high triglyceride concentration, high hepatic lipase activity, and high cholesterol ester transfer protein (CETP) levels. CETP polymorphisms have been reported to be associated with coronary artery disease. In this study, we investigated the relationship between CETP polymorphism and LDL III generation. VLDL1, VLDL2, IDL and LDL subfractions were measured in 87 normal healthy Korean subjects who had been SNP genotyped for Taq1B, I405v and A629C. We found no differences in LDL subfractions and lipoprotein composition between homozygotes for Taq1B2B2, and those for Taq1B1B1 and Taq1B1B2. There were no differences in LDL subfractions and lipoprotein composition between homozygotes for 629AA, and those for 629AC and -629CC. However, homozygotes for 405VV had a significantly lower LDL III concentration and proportion than those for 405II and 405IV. We concluded that, among the Taq1B, I405V and A629C polymorphisms, only the 1405V polymorphism was associated with the concentration and proportion of LDL III. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | Nutritional Sciences | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effects of CETP gene polymorphisms on atherogenic lipoprotein phenotypes in Koreans | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anatomy (해부학) | - |
dc.contributor.googleauthor | Hong Keun Cho | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Jong Eun Lee | - |
dc.contributor.googleauthor | Hakbae Lee | - |
dc.contributor.googleauthor | Hyun Young Park | - |
dc.contributor.googleauthor | Eun Young Cho | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A03883 | - |
dc.contributor.localId | A03146 | - |
dc.relation.journalcode | J02403 | - |
dc.identifier.url | http://www.dbpia.co.kr/Article/1459479 | - |
dc.subject.keyword | LDL Ⅲ | - |
dc.subject.keyword | CETP | - |
dc.subject.keyword | polymorphism | - |
dc.subject.keyword | 1405V | - |
dc.subject.keyword | A629C | - |
dc.subject.keyword | Taq1B | - |
dc.contributor.alternativeName | Lee, Jong Eun | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Cho, Eun Young | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Cho, Eun Young | - |
dc.contributor.affiliatedAuthor | Lee, Jong Eun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 6 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 100 | - |
dc.citation.endPage | 105 | - |
dc.identifier.bibliographicCitation | Nutritional Sciences, Vol.6(2) : 100-105, 2003 | - |
dc.identifier.rimsid | 55793 | - |
dc.type.rims | ART | - |
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