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피부에 국한된 Rosai-Dorfman disease 2예

Other Titles
 Two Cases of Cutaneous Rosai-Dorfman Disease 
Authors
 정혜진  ;  노미령  ;  정기양  ;  이민걸 
Citation
 Korean Journal of Dermatology (대한피부과학회지), Vol.42(4) : 464-468, 2004 
Journal Title
 Korean Journal of Dermatology (대한피부과학회지) 
ISSN
 0494-4739 
Issue Date
2004
Keywords
Rosai-Dorfman disease ; Sinus histiocytosis with massive lymphadenopathy ; Cutaneous involvement
Abstract
Rosai-Dorfman disease (RDD) of sinus histiocytosis with massive lymphadenopathy (SHML) is a benign, idiopathic histiocytic proliferative disorder affecting lymph nodes as well as extranodal sites. It is accompanied by fever, leukocytosis, elevated erythrocyte sedimentation rate, and polyclonal hypergammaglobulinemia. Although cutaneous in RDD is common, a purely cutaneous disease is very rare. Histologic findings show characteristic large, pale, histiocytic cells exhibiting cytophagocytosis (emperipolesis). Immunohistochemically, these histiocytes are positive for S-100 protein and CD68, but negative for CD1a. The etiology is unknown, although it is thought to be a reactive disorder rather than neoplastic. We report two cases of Rosai-Dorfman disease showing involvement limited to the skin.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Roh, Mi Ryung(노미령) ORCID logo https://orcid.org/0000-0002-6285-2490
Lee, Min Geol(이민걸) ORCID logo https://orcid.org/0000-0001-7040-5335
Chung, Kee Yang(정기양) ORCID logo https://orcid.org/0000-0003-3257-0297
Chung, Hye Jin(정혜진)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/112379
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