707 413

Cited 0 times in

임신 1/3분기에 태아 기형 진단을 위한 경복벽 배태아경술 6예

Other Titles
 Transabdominal embryofetoscopy in 6 cases of first trimester prenatal diagnosis for congenital anomalies 
 이국  ;  김청미  ;  채용현  ;  조한별  ;  이현준  ;  이상희  ;  조시현  ;  서석교 
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지), Vol.47(12) : 2351-2358, 2004 
Journal Title
Korean Journal of Obstetrics and Gynecology(대한산부인과학회잡지)
Issue Date
Embryofetoscopy ; Prenatal diagnosis ; Congenital anomalies ; First trimester
Objective: To demonstrate the efficacy of first trimester embryofetoscopy for prenatal diagnosis of congenital anomalies in continuing pregnancies.

Methods: Under ultrasound guidance, six patients at 12+6-14+6 weeks of gestation underwent endoscopic procedures. Indications included history of 2 recurrent major genetic syndromes, history of cleft lip/palate in 2 cases, each one of the patient itself and the previous fetus and each family history of syndactyly and polydactyly. A 1 mm semirigid fiberoptic endoscope with a 18 gauge examination sheath and a single-chip digital camera were used for transabdominal embryofetoscopy.

Results: Excellent visualization of the external fetal anatomy was obtained in 83% of cases (5/6) with the duration of procedures ranging 15 to 40 minutes. A diagnosis of Meckel-Gruber syndrome was made at 13+1 weeks of gestation by visualizing postaxial polydactyly and an occipital encephalocele. Subsequently the pregnancy was terminated. Three full-term infants were delivered with no gross limb or facial abnormalities. Amniotic fluid leakage after the procedure occurred in 2 cases resulting in termination of pregnancy.

Conclusion: Our experiences confirm the efficacy of embryofetoscopy for early diagnosis in the first trimester of pregnancy. Procedure-related risks are to be established by multicenter studies.
Files in This Item:
T200400477.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Cheong Mee(김청미)
Lee, Kook(이국)
Lee, Sang Hee(이상희)
Cho, Si Hyun(조시현) ORCID logo https://orcid.org/0000-0003-2718-6645
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.