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건강한 성인에서 공복 및 식후의 장음 변화 분석과 혈중 5-hydroxytryptamine 농도의 변화에 관한 연구

Other Titles
 Fasting and Postprandial Analysis of Bowel Sounds and Plasma 5-hydroxytryptamine Level 
 정연수  ;  박효진  ;  이상인  ;  김영균  ;  최은주 
 Korean Journal of Gastroenterology, Vol.44(3) : 142-146, 2004 
Journal Title
 Korean Journal of Gastroenterology (대한소화기학회지) 
Issue Date
Bowel sounds ; 5-hydroxytryptamine (5-HT)
Background/Aims: Auscultation of bowel sounds is a traditional technique for evaluating patients with abdominal symptoms. It is, however, subjective and qualitative method in general. Recently, analysis of bowel sounds becomes possible. We analyzed bowel sounds in healthy volunteers and measured platelet depleted plasma 5-hydroxytryptamine (5-HT) that may be associated with postprandial symptoms in irritable bowel syndrome. Methods: We recorded both fasting and postprandial bowel sounds for 30 minutes in 16 healthy volunteers with a sensitive electronic stethoscope attached to a digital recorder. The files were saved in computer as wav files and analyzed with a specialized program. Blood samples were also taken before and 1 hour after meal for 5-HT analysis. Results: Meal challenge made no statistically significant changes in the 5-HT concentrations and all the sound parameters including sound to sound interval, sounds/minute, average of sound amplitudes, sound length, percentage of bowel sounds representing sound clustering and dominant frequency of sounds. Conclusions:Postprandial changes in bowel sounds and plasma 5-HT were insignificant in healthy Korean volunteers.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Gyun(김영균)
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Lee, Sang In(이상인)
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