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Pharmacokinetics of indinavir in Koreans and Caucasians

Authors
 Jun Yong Choi  ;  Kyung Hee Chang  ;  June Myung Kim  ;  Young Goo Song  ;  So Youn Shin  ;  Cheong Ho Cho  ;  Yoon Soo Park 
Citation
 SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, Vol.36(4) : 307-309, 2004 
Journal Title
 SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 
ISSN
 0036-5548 
Issue Date
2004
MeSH
Adult ; Area Under Curve ; Asian Continental Ancestry Group* ; European Continental Ancestry Group* ; HIV Protease Inhibitors/administration & dosage ; HIV Protease Inhibitors/pharmacokinetics* ; Humans ; Indinavir/administration & dosage ; Indinavir/pharmacokinetics* ; Male
Abstract
We evaluated whether the pharmacokinetic parameters of indinavir differ in Koreans and Caucasians. Indinavir was administered orally to 8 healthy Koreans and 4 healthy Caucasians, and plasma indinavir levels were quantified by high performance liquid chromatography. No significant differences were observed in terms of its pharmacokinetic parameters; however, the AUC difference between the 2 groups may be significant for larger sample sizes.
Full Text
http://informahealthcare.com/doi/abs/10.1080/00365540410019697
DOI
10.1080/00365540410019697
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, June Myung(김준명)
Park, Yoon Soo(박윤수)
Song, Young Goo(송영구) ORCID logo https://orcid.org/0000-0002-0733-4156
Shin, So Youn(신소연)
Chang, Kyung Hee(장경희)
Cho, Cheong Ho(조정호)
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111191
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