1 337

Cited 4 times in

Necrosis of carcinoma cells using Co1-xNixFe2O4 and Ba1-xSrxFe12O19 ferrites under alternating magnetic field

Authors
 Dong-Hyun Kim  ;  Kyoung-Nam Kim  ;  and Yong-Keun Lee  ;  In-Bo Shim  ;  Kwang-Mahn Kim 
Citation
 IEEE TRANSACTIONS ON MAGNETICS, Vol.40(4) : 2985-2987, 2004 
Journal Title
IEEE TRANSACTIONS ON MAGNETICS
ISSN
 0018-9464 
Issue Date
2004
Keywords
Iron, ; Ferrites, ; Strontium, ; Magnetic fields, ; Cancer, ; Temperature, ; Magnetic field measurement, ; Heat treatment, ; Hyperthermia, ; Magnetic hysteresis
Abstract
The purpose of this study was to investigate the cell necrosis by the hysteric heating of Co1-xNixFe2O4 and Ba1-xSrxFe12O19 ferrites under external magnetic field with respect to applications in hyperthermic cancer treatments. Co1-xNixFe2O4 and Ba1-xSrxFe12O19 ferrites were synthesized by a sol-gel process. Variation of the temperature as a result of hysteresis heating was measured as a function of the exposure time to the external alternating magnetic field at frequencies of 0.1 ∼ 15 MHz. A human squamous cell carcinoma KB cell line was selected to determine the effect of the synthesized ferrites on the destruction of carcinoma cells in vitro using a methylthiazol tetrazolium bromide (MTT) method. When a CoFe2O4 disc was placed in 0.2 ml of distilled water, the greatest temperature change (ΔT=29.3°C) was observed. More than half of the malignant carcinoma cells were dead after being exposed to the 7-MHz ac magnetic field for 1 h by CoFe2O4 ferrites, while normal cells survived more than 60% of the time.
Full Text
http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=1325707
DOI
10.1109/TMAG.2004.829181
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyoung Nam(김경남)
Kim, Kwang Mahn(김광만) ORCID logo https://orcid.org/0000-0002-5235-0294
Lee, Yong Keun(이용근)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111182
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links