Cited 12 times in
Optimal TE for SPIO-Enhanced Gradient-Recalled Echo MRI for the Detection of Focal Hepatic Lesions
DC Field | Value | Language |
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dc.contributor.author | 김기황 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김주희 | - |
dc.contributor.author | 정재준 | - |
dc.contributor.author | 최진영 | - |
dc.date.accessioned | 2015-06-10T13:05:05Z | - |
dc.date.available | 2015-06-10T13:05:05Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0361-803X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110978 | - |
dc.description.abstract | OBJECTIVE: The objective of our study was to determine the optimal TE for superparamagnetic iron oxide (SPIO)-enhanced gradient-recalled echo (GRE) MRI for the detection of focal hepatic lesions. MATERIALS AND METHODS: Ferucarbotran-enhanced GRE sequences, performed on a 1.5-T MR system, were used to evaluate 131 lesions (38 hepatocellular carcinomas, 37 metastases, 21 hemangiomas, 7 cholangiocarcinomas, 15 cysts, and 13 miscellaneous lesions) at four different TEs: 9, 13.5, 18, and 22.5 milliseconds. The lesion-to-liver signal difference-to-noise ratio (SDNR) was compared among the four GRE sequences by paired Student's t tests and among lesion types by an independent samples Student's t test. The McNemar test was used to compare the sensitivity for the detection of focal hepatic lesions. Wilcoxon's signed rank test was used to compare the subjective lesion conspicuity. RESULTS: The SDNRs of lesions on GRE images obtained at a TE of 13.5 milliseconds (mean +/- SD, 60 +/- 24) were significantly (p < 0.001) higher than those at TEs of 9 (55 +/- 23), 18 (55 +/- 22), and 22.5 milliseconds (47 +/- 19). The SDNR was highest at a TE of 13.5 milliseconds for SPIO-uptake lesions and was comparable on images obtained with TEs of 18 and 13.5 milliseconds for non-SPIO-uptake lesions. The non-SPIO-uptake lesions showed a significantly higher SDNR than the SPIO-uptake lesions at a TE of 22.5 milliseconds (p = 0.007). The overall sensitivity for lesion detection was not significantly different among the four GRE sequences, and the subjective ratings of lesion conspicuity were comparable for images obtained using TEs of 8, 13.5, and 18 milliseconds, but the ratings of lesion conspicuity were significantly lower for images obtained using a TE of 22.5 milliseconds (p < 0.001). CONCLUSION: For ferucarbotran-enhanced MRI, lesion SDNR was highest on images obtained using a TE of 13.5 milliseconds, but the sensitivity and lesion conspicuity were comparable at TEs of 9 and 18 milliseconds. The SDNR of liver lesions varied according to the lesion's potential capability of taking up SPIO agents. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 255~266 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF ROENTGENOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carcinoma, Hepatocellular/diagnosis* | - |
dc.subject.MESH | Contrast Media/administration & dosage | - |
dc.subject.MESH | Cysts/diagnosis* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Ferric Compounds/administration & dosage | - |
dc.subject.MESH | Hemangioma/diagnosis* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Diseases/diagnosis* | - |
dc.subject.MESH | Liver Neoplasms/diagnosis* | - |
dc.subject.MESH | Liver Neoplasms/secondary | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Optimal TE for SPIO-Enhanced Gradient-Recalled Echo MRI for the Detection of Focal Hepatic Lesions | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.contributor.googleauthor | Jin Young Choi | - |
dc.contributor.googleauthor | Sung Ho Park | - |
dc.contributor.googleauthor | Jae-Joon Chung | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.contributor.googleauthor | Donald G. Mitchell | - |
dc.identifier.doi | 10.2214/AJR.05.0706 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00951 | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A03712 | - |
dc.contributor.localId | A04200 | - |
dc.relation.journalcode | J00116 | - |
dc.identifier.eissn | 1546-3141 | - |
dc.identifier.pmid | 16928903 | - |
dc.identifier.url | http://www.ajronline.org/doi/abs/10.2214/AJR.05.0706 | - |
dc.subject.keyword | contrast media | - |
dc.subject.keyword | liver | - |
dc.subject.keyword | liver disease | - |
dc.subject.keyword | MR contrast agents | - |
dc.subject.keyword | MR technique | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.alternativeName | Chung, Jae Joon | - |
dc.contributor.alternativeName | Choi, Jin Young | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Chung, Jae Joon | - |
dc.contributor.affiliatedAuthor | Choi, Jin Young | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 187 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 255 | - |
dc.citation.endPage | 266 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF ROENTGENOLOGY, Vol.187(3) : 255-266, 2006 | - |
dc.identifier.rimsid | 51895 | - |
dc.type.rims | ART | - |
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