Formation of silver incorporated calcium phosphate film for medical applications

Abstract

Calcium phosphate coating layers were formed by electron beam evaporation of hydroxyapatite as an evaporant with and without simultaneous Ar ion bombardments. The Ca/P ratio of film, which determined the biological properties, was controlled by ion beam current. Without ion beam bombardments, the film had the low Ca/P ratio of 1.30, however, the ratio increased to 2.02 by bombarding of Ar ion beam extracted from the end-hall type ion gun set to 0.6 A. Silver incorporated calcium phosphate films were formed by immersing calcium phosphate coated samples in 0.4 M AgNO3 for 30 min, and the Ag doped surface was almost 100% effective in reducing bacteria on contact with respect to controls.