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유방에 만져지는 증상을 가진 환자에서 유방촬영술과 유방초음파가 모두 정상일 때의 임상적 의의

Other Titles
 The Clinical Significance of Normal Mammograms and Normal Sonograms in Patients with Palpable Abnormalities of the Breast 
Authors
 이진화  ;  김은경  ;  윤성국  ;  최순섭  ;  남경진  ;  조세헌  ;  김대철  ;  김정일 
Citation
 Journal of the Korean Society of Radiology, Vol.55(3) : 299-304, 2006 
Journal Title
Journal of the Korean Society of Radiology(대한영상의학회지)
ISSN
 1738-2637 
Issue Date
2006
Keywords
Breast US ; Breast radiography ; comparative studies ; Breast ; abnormalities ; Biopsies
Abstract
Purpose: We wanted to evaluate the clinical significance of normal mammograms and normal sonograms in patients with palpable abnormalities of the breast.

Materials and Methods: From Apr 2003 to Feb 2005, 107 patients with 113 palpable abnormalities who had combined normal sonographic and normal mammographic findings were retrospectively studied. The evaluated parameters included age of the patients, the clinical referrals, the distribution of the locations of the palpable abnormalities, whether there was a past surgical history, the mammographic densities and the sonographic echo patterns (purely hyperechoic fibrous tissue, mixed fibroglandular breast tissue, predominantly isoechoic glandular tissue and isoechoic subcutaneous fat tissue) at the sites of clinical concern, whether there was a change in imaging and/or the physical examination results at follow-up, and whether there were biopsy results. This study period was chosen to allow a follow-up period of at least 12 months.

Results: The patients' ages ranged from 22 to 66 years (mean age: 48.8 years) and 62 (58%) of the 107 patients were between 41 and 50 years old (58%). The most common location of the palpable abnormalities was the upper outer portion of the breast (45%) and most of the mammographic densities were dense patterns (BI-RADS Type 3 or 4: 91%). Our cases showed similar distribution for all the types of sonographic echo patterns. 23 patients underwent biopsy; all the biopsy specimens were benign. For the 84 patients with 90 palpable abnormalities who were followed, there was no interval development of breast cancer in the areas of clinical concern.

Conclusion: Our results suggest that we can follow up and prevent unnecessary biopsies in women with palpable abnormalities when both the mammography and ultrasonography show normal tissue, but this study was limited by its small sample size. Therefore, a larger study will be needed to better define the negative predictive value of combined normal sonographic and mammographic findings.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/110835
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