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Exacerbation of Avellino Corneal Dystrophy After LASIK in North America

Authors
 Christopher S. Banning  ;  Woon Cho Kim  ;  J. Bradley Randleman  ;  Eung Kweon Kim  ;  R. Doyle Stulting 
Citation
 Cornea, Vol.25(4) : 482-484, 2006 
Journal Title
 Cornea 
ISSN
 0277-3740 
Issue Date
2006
Abstract
PURPOSE: To report the first case of Avellino corneal dystrophy exacerbation after LASIK in a white or North American patient. METHODS: Case report and literature review. RESULTS: A 25-year-old white female developed progressive corneal opacities after LASIK. Preoperative examination had revealed only subtle white corneal opacities in each eye. The patient's mother had similar corneal opacities. DNA analysis of the patient revealed a heterozygous mutation at the R124H location in the BIGH3 gene. CONCLUSIONS: LASIK can exacerbate Avellino corneal dystrophy and should be avoided in patients with this condition. A careful history and genetic analysis can identify affected patients and those at risk.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003226-200605000-00022&LSLINK=80&D=ovft
DOI
10.1097/01.ico.0000195949.93695.37
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/110500
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