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안면부와 경부에 발생한 백반증에서 308 nm 엑시머 레이저 요법의 치료 효과

Other Titles
 Therapeutic Effects of 308 nm Excimer Laser in the Treatment of Vitiligo on the Head and Neck Area 
 김도영  ;  이주희  ;  한승경  ;  박윤기 
 Korean Journal of Dermatology (대한피부과학회지), Vol.44(11) : 1290-1297, 2006 
Journal Title
 Korean Journal of Dermatology (대한피부과학회지) 
Issue Date
Excimer laser ; Head and neck ; Vitiligo
Background: The excimer laser has recently been introduced as a new therapeutic modality for vitiligo. However, to date, there have only been a few clinical reports evaluating the therapeutic effects of excimer laser treatment for vitiligo of the head and neck area. Objective: This study was conducted to evaluate the effects of excimer laser therapy on vitiligo of the head and neck area against various clinical parameters. Methods: The 87 patients enrolled in this study were treated with excimer laser monotherapy. We observed the grade of repigmentation after 20 sessions of treatment, and analyzed mean grade of repigmentation with regard to various clinical parameters, to discover determinant factors on therapeutic outcome. Results: Thirty-four of the 87 patients (39.1%) achieved more than 50% repigmentation after or within 20 sessions. The response to treatment was related to the duration of evolution of the vitiligo, type of vitiligo, history of previous treatments, and existence of poliosis within the lesion (respectively, p=0.006, 0.001, < 0.001, 0.004). No relationship could be established between response to the treatment and the following variables: localization of the treated lesion and age of onset (respectively, p=0.42, 0.99). Peri-lesional hyperpigmentation was a relatively common side effect, but other adverse effects were limited and transient. Conclusion: Excimer laser therapy is an effective and safe therapy for vitiligo of the face and neck area. Promising results from excimer laser therapy can be expected in patients who have a short duration of evolution of the vitiligo below 1 year, a focal or generalized type of vitiligo, no previous history of treatment, and a vitiliginous lesion without poliosis.
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1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Park, Yoon Kee(박윤기)
Lee, Ju Hee(이주희) ORCID logo https://orcid.org/0000-0002-1739-5956
Hann, Seung Kyung(한승경)
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