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중등도 및 중증 승모판 협착증 환자에서 경피적 승모판 성형술의 장기 성적 비교

Other Titles
 Comparison of Long-Term(Over 10 Years) Outcome of Percutaneous Mitral Balloon Valvuloplotomy between Moderate and Severe Mitral Stenosis 
 김중선  ;  정보영  ;  강석민  ;  하종원  ;  고영국  ;  최동훈  ;  장양수  ;  정남식  ;  심원흠  ;  조승연  ;  김성순  ;  김창수  ;  남정모 
 KOREAN CIRCULATION JOURNAL, Vol.36(3) : 208-213, 2006 
Journal Title
Issue Date
Mitral stenosis;Balloon valvuloplasty
Background and Objectives: Percutaneous mitral balloon valvuloplotomy (PMV) is a safe and effective procedure for the treatment of mitral stenosis (MS); however, its long-term results according to the severity of MS remain unknown. The aim of this study was to compare the long-term results of PMV between moderate and severe MS.

Subjects and Methods: The immediate and long-term outcomes of 786 patients (198 male, mean age; 43 years) who underwent PMV at a single referral center, between 1988 and 2000, were analyzed. The clinical and echocardiographic data were compared between moderate (n=357) and severe MS (n=429).

Results: Optimal results were gained in 618 (79%) patients, including 80 and 76% moderate and severe MS cases, respectively (p=0.13). Acute complications occurred in 85 patients (11%), but without significant difference between the two groups. After a mean follow-up period of 94 months (range, 6 to 210 month), the 5 year event-free survival rate was better in moderate (88%) than in severe MS (79%), but the 10 year event-free survival rates were no different (65% vs. 65%). Independent predictors for better prognosis were a lower echo score (≤8)(p=0.017, HR=0.67), a larger mitral valve area after the PMV (≥1.7 cm2)(p=0.002, HR=0.65), less mitral regurgitation (III) (p=0.001, HR=0.46) and a lower left atrial pressure (<12 mmHg)(p=0.005, HR=0.80).

Conclusion: The immediate and long-term outcomes of PMV for moderate MS were no better after 9 years than those for severe MS. Therefore, PMV for moderate MS should be considered in selected cases with a favorable MV morphology.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seok Min(강석민) ORCID logo https://orcid.org/0000-0001-9856-9227
Ko, Young Guk(고영국) ORCID logo https://orcid.org/0000-0001-7748-5788
Kim, Sung Soon(김성순)
Nam, Chung Mo(남정모) ORCID logo https://orcid.org/0000-0003-0985-0928
Shim, Won Heum(심원흠)
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Nam Sik(정남식)
Joung, Bo Young(정보영) ORCID logo https://orcid.org/0000-0001-9036-7225
Cho, Seung Yun(조승연)
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
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