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Prediction of Transmural Extent of Infarction with Contrast Echocardiographically Derived Index of Myocardial Blood Flow and Myocardial Blood Volume Fraction: Comparison with Contrast-enhanced Magnetic Resonance Imaging

DC Field Value Language
dc.contributor.author임세중-
dc.contributor.author장양수-
dc.contributor.author정남식-
dc.contributor.author최동훈-
dc.contributor.author최병욱-
dc.contributor.author최의영-
dc.contributor.author하종원-
dc.contributor.author강석민-
dc.contributor.author고영국-
dc.contributor.author박성하-
dc.date.accessioned2015-06-10T12:24:07Z-
dc.date.available2015-06-10T12:24:07Z-
dc.date.issued2006-
dc.identifier.issn0894-7317-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/109735-
dc.description.abstractBACKGROUND: We sought to determine the accuracy of myocardial contrast echocardiography (MCE)-derived index of myocardial blood flow and myocardial blood volume fraction (MBVF) in predicting transmural extent of infarction and wall-motion recovery. METHODS: Low and high mechanical index MCE and contrast-enhanced magnetic resonance imaging were performed 5 to 7 days after successful percutaneous revascularization in 30 patients with acute myocardial infarction and regional wall-motion change was assessed 3 months later. The index of myocardial blood flow was calculated as A x beta (dB/s) using the equation y = A (1 - e(-beta t)), which fits the replenishment curve of low mechanical index MCE. The MBVF (mL/100 g myocardium) was calculated as 100 x 10(relative contrast intensity [CI]/10), using the relative CI by subtracting the cavity CI from the adjacent transmural CI using high mechanical index MCE. The contrast-enhanced magnetic resonance imaging-derived transmural extent of delayed hyperenhancement (DE) in 16 segments were measured and compared with corresponding MCE data. RESULTS: Among 480 segments, 382 measurable segments were subdivided into 5 groups as follows: no DE, 1% to 25% DE, 26% to 50% DE, 51% to 75% DE, and 76% to 100% DE. An increment of the extent of DE was significantly related to a decrement of A x beta (P < .001) and MBVF (P < .001). The optimal cut-off MBVF for predicting greater than 50% DE was 1.92 mL (sensitivity 82%, specificity 73%, P < .01), and persistently dysfunctional motion was 1.81 mL (sensitivity 74%, specificity 75%, P < .01). CONCLUSION: The MCE-derived A x beta and MBVF can be effective predictors of transmural extent of infarction and wall-motion recovery in the reperfused acute myocardial infarction.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1211~1219-
dc.relation.isPartOfJOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBlood Flow Velocity-
dc.subject.MESHBlood Volume*-
dc.subject.MESHContrast Media-
dc.subject.MESHCoronary Circulation*-
dc.subject.MESHEchocardiography/methods*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImage Enhancement/methods-
dc.subject.MESHImage Interpretation, Computer-Assisted/methods-
dc.subject.MESHMagnetic Resonance Imaging/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction/classification-
dc.subject.MESHMyocardial Infarction/complications-
dc.subject.MESHMyocardial Infarction/diagnosis*-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHSeverity of Illness Index*-
dc.subject.MESHVentricular Dysfunction, Left/classification-
dc.subject.MESHVentricular Dysfunction, Left/diagnosis*-
dc.subject.MESHVentricular Dysfunction, Left/etiology-
dc.titlePrediction of Transmural Extent of Infarction with Contrast Echocardiographically Derived Index of Myocardial Blood Flow and Myocardial Blood Volume Fraction: Comparison with Contrast-enhanced Magnetic Resonance Imaging-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorEui-Young Choi-
dc.contributor.googleauthorHye-Sun Seo-
dc.contributor.googleauthorSungha Park-
dc.contributor.googleauthorHyun-Joo Kim-
dc.contributor.googleauthorJeong-Ah Ahn-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorByoung-Wook Choi-
dc.contributor.googleauthorSeok-Min Kang-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1016/j.echo.2006.04.027-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03372-
dc.contributor.localIdA03448-
dc.contributor.localIdA03585-
dc.contributor.localIdA04053-
dc.contributor.localIdA04059-
dc.contributor.localIdA04165-
dc.contributor.localIdA04257-
dc.contributor.localIdA00037-
dc.contributor.localIdA00127-
dc.contributor.localIdA01512-
dc.relation.journalcodeJ01777-
dc.identifier.eissn1097-6795-
dc.identifier.pmid17000359-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0894731706004780-
dc.contributor.alternativeNameRim, Se Joong-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.affiliatedAuthorRim, Se Joong-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorKang, Seok Min-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorPark, Sung Ha-
dc.rights.accessRightsnot free-
dc.citation.volume19-
dc.citation.number10-
dc.citation.startPage1211-
dc.citation.endPage1219-
dc.identifier.bibliographicCitationJOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, Vol.19(10) : 1211-1219, 2006-
dc.identifier.rimsid53386-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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