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외음부 파젯씨병

Other Titles
 Paget`s disease of the vulva 
Authors
 이현철  ;  김영태  ;  김상운  ;  윤보성  ;  남은지  ;  김성훈  ;  김재훈  ;  김재욱  ;  조남훈 
Citation
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지), Vol.49(8) : 1667-1673, 2006 
Journal Title
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지) 
ISSN
 2287-8572 
Issue Date
2006
Keywords
Paget’s disease ; Vulva ; Recurrence
Abstract
Objective: This study of Paget`s disease of the vulva was conducted to evaluate whether the initial presenting symptoms, associated diseases and basic screening studies such as imaging studies and tumor markers could be used to predict the state of the disease, and to investigate whether the state of resection margins, bilaterality of the lesion, and the extent of the resection correlated with recurrence. Methods: This retrospective study was performed on 7 patients diagnosed as Paget`s disease of the vulva from March, 1996 to April, 2006. Results: The average age of the patients was 62 year old (range, form 53 to 70). All patients had been menopaused with sustained inflammation signs, eczematoid skin lesion and pain of the external genitalia. None was related to the associated diseases. Preoperative radiologic imaging and tumor marker levels could not determine the extent of diseases. The patients were observed for a period of 31.6 months in average following surgery, during which the disease recurred in one patient. The factors such as resection margin status, bilaterality of the lesion, and the extent of the resection were not valid for indicating the recurrences. Conclusion: As we have studied, there is limits to predict the recurrence or the state of the disease. Thus leaving enough resection margins for treatment and long term close follow-up should be essential for treatment of patients with Paget`s disease of the vulva.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Hoon(김성훈) ORCID logo https://orcid.org/0000-0002-1645-7473
Kim, Young Tae(김영태) ORCID logo https://orcid.org/0000-0002-7347-1052
Kim, Jae Wook(김재욱)
Kim, Jae Hoon(김재훈) ORCID logo https://orcid.org/0000-0001-6599-7065
Cho, Nam Hoon(조남훈) ORCID logo https://orcid.org/0000-0002-0045-6441
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109376
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