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혈청 요산 농도와 대사증후군과의 관련성

Other Titles
 Relationship between Serum Uric Acid and Metabolic Syndrome 
Authors
 오현주  ;  문상훈  ;  이지원  ;  현혜연  ;  이덕철  ;  이혜리 
Citation
 Journal of the Korean Academy of Family Medicine (가정의학회지), Vol.27(9) : 699-705, 2006 
Journal Title
Journal of the Korean Academy of Family Medicine(가정의학회지)
ISSN
 2005-6443 
Issue Date
2006
Keywords
metabolic syndrome ; uric acid ; cardiovascular ; diseases ; risk factors
Abstract
Background : Although many studies have focused on the association of hyperuricemia with components of metabolic syndrome, there are only few studies of independent relation between uric acid and metabolic syndrome itself. In this study, we evaluated healthy subjects and assessed the relationship of serum uric acid with metabolic syndrome.

Methods : Between January and February of 2005, we evaluated 164 healthy patients who visited a health evaluation center. Patients were evaluated for metabolic syndrome and risk factors were assessed using a questionaire, blood test and physical examination.

Results : Metabolic risk factors significantly increased as uric acid level markedly increased (P<0.05). Even after limiting the variables such as age, sex, smoking, exercise, total cholesterol, low-density lipoprotein cholesterol, and LogCRP, the group with metabolic syndrome had markedly increased uric acid levels than those without metabolic syndrome [Odds ratio 1.494 (95% CI, 1.072∼2.084)].

Conclusion : The number of components of metabolic syndrome increased according to serum uric acid level. Uric acid level was significantly higher in metabolic syndrome than normal. Even after considering health behavior variables such as smoking, alcohol status, and exercise, they showed an independent relationship. Further massive prospective studies on whether collecting serum uric acid level can be used as a screening test or predictor of mortality for early metabolic syndrome and cardiovascular disease will be needed.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Duk Chul(이덕철) ORCID logo https://orcid.org/0000-0001-9166-1813
Lee, Hye Ree(이혜리)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109352
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