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Allergenic tropomyosins and their cross-reactivities

Authors
 Kyoung Yong Jeong  ;  Chein-Soo Hong  ;  Tai-Soon Yong 
Citation
 PROTEIN AND PEPTIDE LETTERS, Vol.13(8) : 835-845, 2006 
Journal Title
PROTEIN AND PEPTIDE LETTERS
ISSN
 0929-8665 
Issue Date
2006
MeSH
Allergens/genetics ; Allergens/immunology* ; Allergens/metabolism ; Amino Acid Sequence ; Animals ; Cross Reactions/immunology* ; Food Hypersensitivity/immunology ; Food Hypersensitivity/metabolism ; Humans ; Molecular Sequence Data ; Sequence Alignment ; Tropomyosin/genetics ; Tropomyosin/immunology* ; Tropomyosin/metabolism
Keywords
Allergen ; cross-reactivity ; tropomyosin
Abstract
The ingestion or inhalation of some proteins may lead to adverse immune reactions. Allergens may trigger allergic reactions in genetically predisposed individuals when they are absorbed through the skin or make contact with mucous membranes. An allergic disease often deteriorates the quality of life and may sometimes be life-threatening due to anaphylactic shock. A number of allergens have been characterized from various multicellular organisms to date. It is thought to be reasonable to pay a special attention to the substance which is highly cross-reactive and which causes adverse responses in the molecules that Tropomyosin has been described as an important food allergen in shrimp, lobster, crab, oysters, squid, and other invertebrates. Allergic reactions to shellfish and mollusks are often cross-reactive, which may be explained by the highly conserved amino aci Much effort has been made to characterize these allergenic tropomyosins from various sources. We will discuss the physicochemical characteristics and the potential application of tropomyosin for the diagnosis and therapeutics of allergic disorders.
Full Text
http://www.eurekaselect.com/57396/article
DOI
10.2174/092986606777841244
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Tropica Medicine (열대의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Yong, Tai Soon(용태순) ORCID logo https://orcid.org/0000-0002-3445-0769
Jeong, Kyoung Yong(정경용) ORCID logo https://orcid.org/0000-0001-9887-1426
Hong, Chein Soo(홍천수)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109329
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