Cited 16 times in
Systematic analysis of cDNA microarray-based CGH.
DC Field | Value | Language |
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dc.contributor.author | 라선영 | - |
dc.contributor.author | 안성환 | - |
dc.contributor.author | 양상화 | - |
dc.contributor.author | 정현철 | - |
dc.contributor.author | 정희철 | - |
dc.date.accessioned | 2015-06-10T11:58:03Z | - |
dc.date.available | 2015-06-10T11:58:03Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1107-3756 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108946 | - |
dc.description.abstract | cDNA microarray-based CGH (Microarray-CGH) is a useful technique for detecting genomic aberrations with a high resolution. However, the criteria for determining a genomic alteration have not been determined. We evaluated the genome-wide measurement of copy number of each gene in normal gastric and placenta tissues with both sex-matched, direct and sex-mismatched, indirect designs using 17K cDNA microarray. The results revealed the range of genomic copy number of normal tissues to be ±0.3 of the log2 ratio (gain >0.3, loss <−0.3) in the autosomal genes with direct and indirect designs. The copy number at a gene level from the X chromosomal genes using the direct and indirect sex-mismatched designs was ±0.68 of the log2 ratio (amplification >0.68, deletion <−0.68). In summary, the suggested method can be used as a guideline for analysis of genomic aberration using a Microarray-CGH in both direct and indirect designs. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 261~267 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Chromosomes, Human/genetics | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Genome, Human/genetics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | In Situ Hybridization, Fluorescence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Nucleic Acid Hybridization/methods* | - |
dc.subject.MESH | Oligonucleotide Array Sequence Analysis* | - |
dc.title | Systematic analysis of cDNA microarray-based CGH. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Chan Hee Park | - |
dc.contributor.googleauthor | Ha Jin Jeong | - |
dc.contributor.googleauthor | Yeon Ho Choi | - |
dc.contributor.googleauthor | Sang Cheol Kim | - |
dc.contributor.googleauthor | Hei Chul Jeong | - |
dc.contributor.googleauthor | Kyu Hyun Park | - |
dc.contributor.googleauthor | Gui Yeon Lee | - |
dc.contributor.googleauthor | Tae Soo Kim | - |
dc.contributor.googleauthor | Sang Wha Yang | - |
dc.contributor.googleauthor | Sung Whan Ahn | - |
dc.contributor.googleauthor | Yang Seok Kim | - |
dc.contributor.googleauthor | Sun Young Rha | - |
dc.contributor.googleauthor | Hyun Cheol Chung | - |
dc.identifier.doi | 10.3892/ijmm.17.2.261 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02288 | - |
dc.contributor.localId | A03773 | - |
dc.contributor.localId | A02239 | - |
dc.contributor.localId | A01316 | - |
dc.contributor.localId | A03794 | - |
dc.relation.journalcode | J01132 | - |
dc.identifier.eissn | 1791-244X | - |
dc.identifier.pmid | 16391824 | - |
dc.identifier.url | http://www.spandidos-publications.com/ijmm/17/2/261 | - |
dc.contributor.alternativeName | Rha, Sun Young | - |
dc.contributor.alternativeName | An, Sung Whan | - |
dc.contributor.alternativeName | Yang, Sang Hwa | - |
dc.contributor.alternativeName | Chung, Hyun Cheol | - |
dc.contributor.alternativeName | Jeung, Hei Cheul | - |
dc.contributor.affiliatedAuthor | Yang, Sang Hwa | - |
dc.contributor.affiliatedAuthor | Chung, Hyun Cheol | - |
dc.contributor.affiliatedAuthor | An, Sung Whan | - |
dc.contributor.affiliatedAuthor | Rha, Sun Young | - |
dc.contributor.affiliatedAuthor | Jeung, Hei Cheul | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 17 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 261 | - |
dc.citation.endPage | 267 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Vol.17(2) : 261-267, 2006 | - |
dc.identifier.rimsid | 50357 | - |
dc.type.rims | ART | - |
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