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Estimated prevalence and risk factor for age-related maculopathy

Authors
 Mi In Roh  ;  Ji Hyun Kim  ;  Suk Ho Byeon  ;  Hyoung Jun Koh  ;  Sung Chul Lee  ;  Oh Woong Kwon 
Citation
 Yonsei Medical Journal, Vol.49(6) : 931-941, 2008 
Journal Title
 Yonsei Medical Journal 
ISSN
 0513-5796 
Issue Date
2008
Abstract
PURPOSE: To assess the estimate prevalence and risk factors for age-related maculopathy (ARM) in Seoul, Korea. PATIENTS AND METHODS: We examined 9,530 subjects with, 40 years of age or older between January 2006 and December 2006 in Seoul, Korea. Subjects underwent fundus photography, clinical examinations (including blood analyses), and completed detailed questionnaires. Fundus images were graded according to definitions from the Wisconsin Age-Related Maculopathy Grading System. RESULTS: ARM was present in 235 subjects, corresponding to an estimate prevalence of 2.46%. Hepatitis B infection (positive status for HBsAg and HBcAb), serum triglyceride levels and high density lipoprotein levels remained as significant risk factors after age-adjustment. Multivariate analyses showed that the prevalence of ARM was significantly higher in older subjects [odds ratio (OR) 1.134; 95% CI 1.114-1.154] and those who were seropositive for hepatitis B surface antigen (OR 2.566; 95% CI 1.519-4.335). CONCLUSION: The estimated prevalence of ARM was 2.46%. Age and hepatitis B infection may increase the risk of ARM.
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DOI
10.3349/ymj.2008.49.6.931
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실)
Yonsei Authors
고형준(Koh, Hyoung Jun)
권오웅(Kwon, Oh Woong)
노미인(Roh, Mi In)
변석호(Byeon, Suk Ho) ORCID logo https://orcid.org/0000-0001-8101-0830
이성철(Lee, Sung Chul) ORCID logo https://orcid.org/0000-0001-9438-2385
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108420
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