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Estimated prevalence and risk factor for age-related maculopathy

 Mi In Roh  ;  Ji Hyun Kim  ;  Suk Ho Byeon  ;  Hyoung Jun Koh  ;  Sung Chul Lee  ;  Oh Woong Kwon 
 Yonsei Medical Journal, Vol.49(6) : 931-941, 2008 
Journal Title
 Yonsei Medical Journal 
Issue Date
Adult ; Age Factors ; Aged ; Female ; Hepatitis B/complications ; Humans ; Korea/epidemiology ; Lipoproteins, HDL/blood ; Macular Degeneration/blood ; Macular Degeneration/epidemiology* ; Macular Degeneration/etiology ; Male ; Middle Aged ; Risk Factors ; Triglycerides/blood
Age-related maculopathy ; hepatitis B ; triglyceride ; high-density lipoprotein
PURPOSE: To assess the estimate prevalence and risk factors for age-related maculopathy (ARM) in Seoul, Korea. PATIENTS AND METHODS: We examined 9,530 subjects with, 40 years of age or older between January 2006 and December 2006 in Seoul, Korea. Subjects underwent fundus photography, clinical examinations (including blood analyses), and completed detailed questionnaires. Fundus images were graded according to definitions from the Wisconsin Age-Related Maculopathy Grading System. RESULTS: ARM was present in 235 subjects, corresponding to an estimate prevalence of 2.46%. Hepatitis B infection (positive status for HBsAg and HBcAb), serum triglyceride levels and high density lipoprotein levels remained as significant risk factors after age-adjustment. Multivariate analyses showed that the prevalence of ARM was significantly higher in older subjects [odds ratio (OR) 1.134; 95% CI 1.114-1.154] and those who were seropositive for hepatitis B surface antigen (OR 2.566; 95% CI 1.519-4.335). CONCLUSION: The estimated prevalence of ARM was 2.46%. Age and hepatitis B infection may increase the risk of ARM.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kwon, Oh Woong(권오웅)
Roh, Mi In(노미인)
Byeon, Suk Ho(변석호) ORCID logo https://orcid.org/0000-0001-8101-0830
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
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