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Nanohybrids via a polycation-based nanoemulsion method for dual-mode detection of human mesenchymal stem cells

DC Field Value Language
dc.contributor.author서진석-
dc.contributor.author양재문-
dc.contributor.author허용민-
dc.date.accessioned2015-05-19T17:28:36Z-
dc.date.available2015-05-19T17:28:36Z-
dc.date.issued2008-
dc.identifier.issn0959-9428-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108219-
dc.description.abstractFluorescent polycation-coated magnetic nanohybrids (FPMNs) were synthesized for the marking of human mesenchymal stem cells (hMSCs) and non-invasive tracking by both magnetic resonance (MR) and optical imaging. FPMNs were prepared by a polycation-based nanoemulsion method using magnetic nanocrystals (MNCs) as MR probes and polycationic polyethylenimine (PEI) which not only enhanced the affinity for hMSCs but also increased colloidal stability in the aqueous phase. Polycation-coated magnetic nanohybrids (PMNs) were further conjugated with a fluorescent dye (fluorescein isothiocyanate) to serve as optical imaging agents. FPMNs exhibited excellent colloidal stability and biocompatibility as well as high affinity for hMSCs. MR and optical images of hMSCs treated with FPMNs clearly demonstrated abundant potential as brilliant dual-mode imaging agents.-
dc.description.statementOfResponsibilityopen-
dc.format.extent4402~4407-
dc.relation.isPartOfJOURNAL OF MATERIALS CHEMISTRY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleNanohybrids via a polycation-based nanoemulsion method for dual-mode detection of human mesenchymal stem cells-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorSung-Baek Seo-
dc.contributor.googleauthorJaemoon Yang-
dc.contributor.googleauthorEun-Sook Lee-
dc.contributor.googleauthorYukyung Jung-
dc.contributor.googleauthorKyujung Kim-
dc.contributor.googleauthorSang-Yup Lee-
dc.contributor.googleauthorDonghyun Kim-
dc.contributor.googleauthorJin-Suck Suh-
dc.contributor.googleauthorYong-Min Huh-
dc.contributor.googleauthorSeungjoo Haam-
dc.identifier.doi10.1039/B804544E-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02315-
dc.contributor.localIdA01916-
dc.contributor.localIdA04359-
dc.relation.journalcodeJ01571-
dc.identifier.urlhttp://pubs.rsc.org/en/content/articlelanding/2008/jm/b804544e#!divAbstract-
dc.contributor.alternativeNameSuh, Jin Suck-
dc.contributor.alternativeNameYang, Jae Moon-
dc.contributor.alternativeNameHuh, Yong Min-
dc.contributor.affiliatedAuthorYang, Jae Moon-
dc.contributor.affiliatedAuthorSuh, Jin Suck-
dc.contributor.affiliatedAuthorHuh, Yong Min-
dc.rights.accessRightsnot free-
dc.citation.volume18-
dc.citation.number37-
dc.citation.startPage4402-
dc.citation.endPage4407-
dc.identifier.bibliographicCitationJOURNAL OF MATERIALS CHEMISTRY , Vol.18(37) : 4402-4407, 2008-
dc.identifier.rimsid35257-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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