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Hollow silica nanocontainers as drug delivery vehicles.

DC Field Value Language
dc.contributor.author서진석-
dc.contributor.author양재문-
dc.contributor.author윤호근-
dc.contributor.author허용민-
dc.date.accessioned2015-05-19T17:28:22Z-
dc.date.available2015-05-19T17:28:22Z-
dc.date.issued2008-
dc.identifier.issn0743-7463-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108212-
dc.description.abstractNovel hollow silica nanoparticles (HSNPs) for drug delivery vehicles were synthesized using silica-coated magnetic assemblies, which are composed of a number of Fe(3)O(4) nanocrystals, as templates. The core cavity was obtained by removal of Fe(3)O(4) phase with hydrochloric acid and subsequent calcination at a high temperature. HSNPs were modified by amine in order to introduce positive surface charge and further PEGylated for increased solubility in aqueous medium. Doxorubicin as a model drug was loaded into the HSNPs, and notable sustained drug release from HSNPs was demonstrated.-
dc.description.statementOfResponsibilityopen-
dc.format.extent3417~3421-
dc.relation.isPartOfLANGMUIR-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHDoxorubicin/administration & dosage-
dc.subject.MESHDrug Delivery Systems-
dc.subject.MESHFerric Compounds-
dc.subject.MESHNanocapsules/chemistry*-
dc.subject.MESHSilicon Dioxide*-
dc.subject.MESHStructure-Activity Relationship-
dc.titleHollow silica nanocontainers as drug delivery vehicles.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Biochemistry & Molecular Biology (생화학,분자생물학)-
dc.contributor.googleauthorJaemoon Yang-
dc.contributor.googleauthorJaewon Lee-
dc.contributor.googleauthorJinyoung Kang-
dc.contributor.googleauthorKwangyeol Lee-
dc.contributor.googleauthorJin-Suck Suh-
dc.contributor.googleauthorHo-Geun Yoon-
dc.contributor.googleauthorYong-Min Huh-
dc.contributor.googleauthorSeungjoo Haam-
dc.identifier.doi10.1021/la701688t-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01916-
dc.contributor.localIdA02625-
dc.contributor.localIdA04359-
dc.contributor.localIdA02315-
dc.relation.journalcodeJ02155-
dc.identifier.eissn1520-5827-
dc.identifier.pmid18324841-
dc.identifier.urlhttp://pubs.acs.org/doi/abs/10.1021/la701688t-
dc.subject.keywordDoxorubicin/administration & dosage-
dc.subject.keywordDrug Delivery Systems-
dc.subject.keywordFerric Compounds-
dc.subject.keywordNanocapsules/chemistry*-
dc.subject.keywordSilicon Dioxide*-
dc.subject.keywordStructure-Activity Relationship-
dc.contributor.alternativeNameSuh, Jin Suck-
dc.contributor.alternativeNameYang, Jae Moon-
dc.contributor.alternativeNameYoon, Ho Geun-
dc.contributor.alternativeNameHuh, Yong Min-
dc.contributor.affiliatedAuthorSuh, Jin Suck-
dc.contributor.affiliatedAuthorYoon, Ho Geun-
dc.contributor.affiliatedAuthorHuh, Yong Min-
dc.contributor.affiliatedAuthorYang, Jae Moon-
dc.rights.accessRightsnot free-
dc.citation.volume24-
dc.citation.number7-
dc.citation.startPage3417-
dc.citation.endPage3421-
dc.identifier.bibliographicCitationLANGMUIR, Vol.24(7) : 3417-3421, 2008-
dc.identifier.rimsid35255-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
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