소아 청소년 간질에서 토피라메이트와 관련된 인지 기능 장애

Abstract

Topiramate, one of the newer antiepileptic drugs with multiple mechanisms of action and broad spectrum effecicacy, has been proven to be effective in the treatment of a wide range of seizure types in children and adolescents. However, the major concern with respect or topiramate is that many patients have cognitive side effects. So we reviewed previous reports for the cognitive function related to topiramate. In conclusion, slow titlation and low dose monotherapy could de decreased cognitive side effects related to topiramate.