교감신경 피부반응에서 하루주기 리듬의 영향

Abstract

Objectives: To determine the influence of circadian rhythm on amplitude and latency of SSR (sympatheticskin response)Methods: Thirty healthy adults who have no disease in sympathetic and other nerve systems participatedin this study. We recorded the SSR 3 times, in the morning (7:30 am), afternoon (12:30 pm) and evening(5:30 pm). We attached the active electrode on the left palm and reference electrode on the back of theleft hand and ground on the left forearm. We stimulated the right median nerve at wrist three times. Toavoid habituation, intermission between stimuli were more than 1 min and we measured onset latency andpeak to peak amplitude.Results: Average latency of SSR was recorded 1.49±0.12 sec in the morning, 1.48±0.13 sec in theafternoon and 1.46±0.14 sec in the evening. In addition, average amplitudes were recorded 1.97±1.25mV, 1.68±0.99 mV and 1.61±0.93 mV respectively. The average latency and amplitude were greater inthe morning compared to the result in the afternoon and evening, but not statistically significant. Therewas no significant difference between men and women.Conclusion: Latency of SSR was not affected by the change of circadian rhythm. However, not onlyamplitude has a tendency to be increased in the morning but also latency has a tendency to be shortenedin the evening, which should be considered when analyzing the result of SSR.