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유전자검사를 이용한 대량 희생자 개인식별에서의 통계적 해석

Other Titles
 Statistical Interpretation in Making DNA-based Identifications of Mass Victims 
Authors
 신경진  ;  이환영  ;  양우익  ;  하은호 
Citation
 Korean Journal of Legal Medicine (대한법의학회지), Vol.32(1) : 55-60, 2008 
Journal Title
Korean Journal of Legal Medicine(대한법의학회지)
ISSN
 1225-0589 
Issue Date
2008
Keywords
mass victims ; kinship ; relatives ; probability ; likelihood ; allele drop-out ; cold hit
Abstract
DNA profiles have been increasingly used as the most reliable means to identify remains from war or mass disaster. To establish the identity with such a large set of victims, special care should be taken to correlate remains with correct family references while avoiding coincidental match between non-relatives. Therefore we address here relevant statistical and combinatorial issues in the DNA identification of mass victims. A simple and general formula for the likelihood ratio governing any potential kinship between two DNA profiles was presented, and for that purpose, the probabilities that a given relative and an individual share autosomal identical-bydescent alleles were calculated. In addition, a method dealing with the allele drop-out in kinship analysis and the estimation of a cold hit were discussed.
Files in This Item:
T200801068.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Forensic Medicine (법의학과) > 1. Journal Papers
Yonsei Authors
Shin, Kyoung Jin(신경진) ORCID logo https://orcid.org/0000-0002-1059-9665
Lee, Hwan Young(이환영)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107342
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