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림프종 환자에서 양전자단층촬영술상 발견된 비기능성 뇌하수체선종 1예

Other Titles
 Non-functional Pituitary Adenoma Detected on 18F-fluorodeoxyglucose Positron Emission Tomography (18F-FDG-PET) in a Patient with Mucosa-associated Lymphoid Tissue Lymphoma 
Authors
 이진하  ;  한승진  ;  박세은  ;  조미애  ;  정준원  ;  윤미진  ;  이유미  ;  이은직  ;  임승길 
Citation
 Endocrinology and Metabolism (대한내분비학회지), Vol.23(2) : 137-141, 2008 
Journal Title
 Endocrinology and Metabolism (대한내분비학회지) 
ISSN
 2093-596X 
Issue Date
2008
Keywords
lymphoma ; non-functioning pituitary adenoma ; PET
Abstract
Magnetic resonance imaging (MRI) is the modality of choice for the detection and characterization of a pituitary adenoma. Uptake of 18F-fluorodeoxyglucose (FDG) by intrasellar tumors, including pituitary adenomas, has been reported in several previous studies. We report a case where a pituitary adenoma was detected on FDG-positron emission tomography(PET), but the tumor was not detected with the use of sellar MRI. A 31-year-old woman was referred to the clinic due to a focal increase of FDG uptake at the pituitary fossa seen on whole body FDG-PET. The patient was receiving chemotherapy due to a recurred B-cell lymphoma of the mucosa-associated lymphoid tissue type. Subsequently, sellar MRI was performed, and images showed a small non-enhancing heterogenous cystic lesion in the midline of the pituitary gland, radiologically suggestive of a Rathke`s cleft cyst. However, sellar MRI failed to identify a lesion consistent with a pituitary tumor that corresponded to the site of increased FDG uptake detected by the use of PET, despite the inclusion of a dynamic contrast enhanced sequence. Despite the negative findings of the MRI examination, basal and stimulated levels of the GnRH free α-subunit were profoundly increased. Therefore, we suspected the presence of a non-functional pituitary tumor in addition to a Rathke`s cleft cyst, rather than pituitary involvement of a lymphoma, based on the hormone levels and PET scan findings.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers
Yonsei Authors
Park, Se Eun(박세은)
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
Rhee, Yumie(이유미) ORCID logo https://orcid.org/0000-0003-4227-5638
Lee, Eun Jig(이은직) ORCID logo https://orcid.org/0000-0002-9876-8370
Lee, Jin Ha(이진하)
Lim, Sung Kil(임승길)
Chung, Joo Won(정주원)
Cho, Mi Ae(조미애)
Han, Seung Jin(한승진)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107329
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