Cited 76 times in
Enhanced chondrogenic responses of articular chondrocytes onto porous silk fibroin scaffolds treated with microwave-induced argon plasma
DC Field | Value | Language |
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dc.contributor.author | 나동균 | - |
dc.contributor.author | 박종철 | - |
dc.contributor.author | 백현숙 | - |
dc.date.accessioned | 2015-05-19T16:52:44Z | - |
dc.date.available | 2015-05-19T16:52:44Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0257-8972 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107110 | - |
dc.description.abstract | Silk fibroin (SF) as a naturally occurring degradable fibrous protein with unique mechanical properties, excellent biocompatibility and processability has demonstrated strong potential for skeletal tissue engineering. Recent studies has mostly focused on nanofibrous SF (NSF) as a novel chondrogenic scaffold since its structure is very similar to collagen fibrous structure of natural extracellular matrix (ECM). However, less attention has been paid to the surface modification of NSF scaffolds by microwave-induced argon plasma. The present study was based on the hypothesis that plasma treatment to 3-D porous electrospun NSF scaffolds would improve cell growth, chondrogenicity and new cartilage-specific ECM formation of chondrocytes. It was found that plasma treatment could induce an essential modification of the surface of electrospun NSF scaffolds. The attachment and proliferation of human articular chondrocytes onto the surface-modified NSF scaffolds were significantly increased with a concomitant increase in the glycosaminoglycan synthesis. These results suggest that porous NSF scaffolds treated with microwave-induced plasma may be effective for enhancing the cellular behaviors and chondrogenic differentiation of chondrocytes and further be potentially used to cartilage tissue engineering | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 5794~5797 | - |
dc.relation.isPartOf | SURFACE & COATINGS TECHNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Enhanced chondrogenic responses of articular chondrocytes onto porous silk fibroin scaffolds treated with microwave-induced argon plasma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Plastic Surgery & Reconstructive Surgery (성형외과학) | - |
dc.contributor.googleauthor | Hyun Sook Baek | - |
dc.contributor.googleauthor | Young Hwan Park | - |
dc.contributor.googleauthor | Chang Seok Ki | - |
dc.contributor.googleauthor | Jong-Chul Park | - |
dc.contributor.googleauthor | Dong Kyun Rah | - |
dc.identifier.doi | 10.1016/j.surfcoat.2008.06.154 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01229 | - |
dc.contributor.localId | A01662 | - |
dc.contributor.localId | A01843 | - |
dc.relation.journalcode | J02698 | - |
dc.identifier.eissn | 1879-3347 | - |
dc.identifier.pmid | Nanofibrous silk fibroin ; Microwave-induced argon plasma ; Chondrocytes ; CartilageTissue engineering | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0257897208005574 | - |
dc.subject.keyword | Nanofibrous silk fibroin | - |
dc.subject.keyword | Microwave-induced argon plasma | - |
dc.subject.keyword | Chondrocytes | - |
dc.subject.keyword | CartilageTissue engineering | - |
dc.contributor.alternativeName | Rah, Dong Kyun | - |
dc.contributor.alternativeName | Park, Jong Chul | - |
dc.contributor.alternativeName | Baek, Hyun Sook | - |
dc.contributor.affiliatedAuthor | Rah, Dong Kyun | - |
dc.contributor.affiliatedAuthor | Park, Jong Chul | - |
dc.contributor.affiliatedAuthor | Baek, Hyun Sook | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 202 | - |
dc.citation.number | 22-23 | - |
dc.citation.startPage | 5794 | - |
dc.citation.endPage | 5797 | - |
dc.identifier.bibliographicCitation | SURFACE & COATINGS TECHNOLOGY, Vol.202(22-23) : 5794-5797, 2008 | - |
dc.identifier.rimsid | 49543 | - |
dc.type.rims | ART | - |
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