123 188

Cited 5 times in

Report of aids-related lymphoma in South Korea

Authors
 Jin-Soo Kim  ;  Seok Jin Kim  ;  Jin-Seok Kim  ;  Eun Sun Kim  ;  Ho-Jin Shin  ;  Joo Seop Chung  ;  Yoo-Hong Min  ;  Moon Hee Lee  ;  Young Jin Choi  ;  Soo-Mee Bang  ;  Jung A Kim  ;  Goon Jae Cho  ;  Hyun-Sook Chi  ;  Seong Soo Jang  ;  Chan Jeoung Park  ;  Cheolwon Suh  ;  Chong Won Park  ;  Chul Soo Kim 
Citation
 JAPANESE JOURNAL OF CLINICAL ONCOLOGY, Vol.38(2) : 134-139, 2008 
Journal Title
 JAPANESE JOURNAL OF CLINICAL ONCOLOGY 
ISSN
 0368-2811 
Issue Date
2008
MeSH
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use* ; Antiretroviral Therapy, Highly Active* ; Chemotherapy, Adjuvant ; Female ; Humans ; Korea/epidemiology ; Lymphoma, AIDS-Related/drug therapy ; Lymphoma, AIDS-Related/epidemiology* ; Lymphoma, AIDS-Related/radiotherapy ; Lymphoma, AIDS-Related/therapy* ; Lymphoma, B-Cell/epidemiology ; Lymphoma, B-Cell/therapy ; Lymphoma, T-Cell/epidemiology ; Lymphoma, T-Cell/therapy ; Male ; Middle Aged ; Radiotherapy, Adjuvant ; Retrospective Studies ; Survival Analysis ; Treatment Outcome
Keywords
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use* ; Antiretroviral Therapy, Highly Active* ; Chemotherapy, Adjuvant ; Female ; Humans ; Korea/epidemiology ; Lymphoma, AIDS-Related/drug therapy ; Lymphoma, AIDS-Related/epidemiology* ; Lymphoma, AIDS-Related/radiotherapy ; Lymphoma, AIDS-Related/therapy* ; Lymphoma, B-Cell/epidemiology ; Lymphoma, B-Cell/therapy ; Lymphoma, T-Cell/epidemiology ; Lymphoma, T-Cell/therapy ; Male ; Middle Aged ; Radiotherapy, Adjuvant ; Retrospective Studies ; Survival Analysis ; Treatment Outcome
Abstract
BACKGROUND: The prevalence of AIDS-related lymphoma (ARL) is increasing in South Korea. The aim of this study is to identify the clinical features of ARL in South Korea. METHODS: From 1998 through 2006, we retrospectively analysed a total of 23 cases of ARL from seven institutions. RESULTS: The patients consisted of 20 males and 3 females at a median age of 40 (range, 20-72) on diagnosis of AIDS. ARL developed at their median age of 41 (range, 24-72). The histological diagnosis was aggressive B cell lymphoma in the majority, but rare T cell and NK/T cell lymphoma were also included. Ten of 23 (43.5%) was receiving highly active anti-retroviral therapy (HAART) before the diagnosis of ARL. Fifteen of twenty-three patients were given combination chemotherapy with/without radiation, four were given radiation alone, and four did not receive any treatment against medical advice. Of 20 patients followed-up, nine were alive in remission, two alive in disease, one died of treatment related complication, four died of progressive lymphoma, four died of AIDS related causes. The response to treatment included CR in eight (44.4%), PR in four (22.2%) and PD in three (16.7%). The response to HARRT was evaluable in 13 patients based on CD4+ cell count and HIV viral load, among which nine (69.2%) responded. Estimated median survival time was 43.9 months. CONCLUSIONS: Although the population of patients is small, this is the first clinical data analyses of Korean ARL patients. As a substantial portion of the patients remains alive disease free, the impact of HAART on the clinical course of ARL needs further follow-up and evaluation.
Files in This Item:
T200800789.pdf Download
DOI
10.1093/jjco/hym168
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jin Seok(김진석) ORCID logo https://orcid.org/0000-0001-8986-8436
Min, Yoo Hong(민유홍) ORCID logo https://orcid.org/0000-0001-8542-9583
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107055
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse