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Intra-arterial thrombolytic therapy for hyperacute ischemic stroke caused by tandem occlusion

DC FieldValueLanguage
dc.contributor.author김동익-
dc.contributor.author김동준-
dc.contributor.author김응엽-
dc.contributor.author변준수-
dc.contributor.author서상현-
dc.contributor.author정진영-
dc.contributor.author허지회-
dc.date.accessioned2015-05-19T16:50:01Z-
dc.date.available2015-05-19T16:50:01Z-
dc.date.issued2008-
dc.identifier.issn1015-9770-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/107028-
dc.description.abstractBACKGROUND: Tandem occlusion of the arteries at the extracranial and intracranial segments is a unique cause of ischemic stroke and is often associated with a poor prognosis. Although tandem occlusion is occasionally found during intra-arterial thrombolysis (IAT), as of yet no clear therapeutic strategy has been elucidated. METHODS: After identifying distal intradural (DIL) and proximal extradural lesions (PEL) as well as the collateral state and clot burden, IAT was performed primarily targeting DIL by navigation of the microcatheter through the PEL or a collateral pathway. RESULTS: Among 147 consecutive patients who were treated with IAT for hyperacute ischemic stroke, 13 (11.4%) were identified to have tandem occlusion as the cause of stroke. Navigation of a microcatheter through occluded PEL (internal carotid artery/vertebral artery) or a collateral pathway (anterior communicating artery) to the DIL was successful in 9 patients. Of them, recanalization of the DIL could be achieved in 8 (89%). The overall recanalization rate among all patients with tandem occlusion was (62%, 8/13). A good functional outcome (modified Rankin score <or=2) at 3 months was noted in 6 patients (46.2%). CONCLUSIONS: Tandem occlusion may be successfully managed by strategic thrombolysis of the DIL as the primary therapeutic target for IAT. By this strategy, the ischemic brain could be effectively and rapidly perfused.-
dc.description.statementOfResponsibilityopen-
dc.format.extent184~189-
dc.relation.isPartOfCerebrovascular Diseases-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleIntra-arterial thrombolytic therapy for hyperacute ischemic stroke caused by tandem occlusion-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorDong Joon Kim-
dc.contributor.googleauthorDong Ik Kim-
dc.contributor.googleauthorJoon Soo Byun-
dc.contributor.googleauthorJin Young Jung-
dc.contributor.googleauthorSang Hyun Suh-
dc.contributor.googleauthorEung Yeop Kim-
dc.contributor.googleauthorJi Hoe Heo-
dc.identifier.doi10.1159/000145326-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00408-
dc.contributor.localIdA00410-
dc.contributor.localIdA00832-
dc.contributor.localIdA01858-
dc.contributor.localIdA01886-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ00506-
dc.identifier.urlhttp://www.karger.com/Article/FullText/145326-
dc.contributor.alternativeNameKim, Dong Ik-
dc.contributor.alternativeNameKim, Dong Joon-
dc.contributor.alternativeNameKim, Eung Yeop-
dc.contributor.alternativeNameByun, Joon Soo-
dc.contributor.alternativeNameSuh, Sang Hyun-
dc.contributor.alternativeNameJung, Jin Young-
dc.contributor.alternativeNameHeo, Ji Hoe-
dc.contributor.affiliatedAuthorKim, Dong Ik-
dc.contributor.affiliatedAuthorKim, Dong Joon-
dc.contributor.affiliatedAuthorKim, Eung Yeop-
dc.contributor.affiliatedAuthorByun, Joon Soo-
dc.contributor.affiliatedAuthorSuh, Sang Hyun-
dc.contributor.affiliatedAuthorHeo, Ji Hoe-
dc.rights.accessRightsnot free-
dc.citation.volume26-
dc.citation.number2-
dc.citation.startPage184-
dc.citation.endPage189-
dc.identifier.bibliographicCitationCerebrovascular Diseases, Vol.26(2) : 184-189, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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