Cited 22 times in
A cyclic RGD-coated peptide nanoribbon as a selective intracellular nanocarrier
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권오준 | - |
dc.contributor.author | 김평환 | - |
dc.contributor.author | 윤채옥 | - |
dc.date.accessioned | 2015-05-19T16:46:07Z | - |
dc.date.available | 2015-05-19T16:46:07Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1477-0520 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106909 | - |
dc.description.abstract | We have synthesized a peptide-based supramolecular building block consisting of a cyclic Arg-Gly-Asp (cRGD) peptide segment and a beta-sheet-forming peptide segment. The block peptide was shown to self-assemble into a cRGD-coated nanoribbon structure, as revealed by circular dichroism (CD), dynamic light scattering (DLS), and transmission electron microscopy (TEM) studies. We have shown that this cRGD-coated nanoribbon can encapsulate hydrophobic guest molecules and deliver them into cells. Colocalization of the nanoribbon with LysoTracker and the selective intracellular delivery results suggests that the cRGD-coated nanoribbon is likely to be internalized into the cells through integrin receptors. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1944~1948 | - |
dc.relation.isPartOf | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Amino Acid Sequence | - |
dc.subject.MESH | Circular Dichroism | - |
dc.subject.MESH | HeLa Cells | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Jurkat Cells | - |
dc.subject.MESH | Microscopy, Electron, Transmission | - |
dc.subject.MESH | Molecular Sequence Data | - |
dc.subject.MESH | Nanostructures* | - |
dc.subject.MESH | Oligopeptides/chemistry* | - |
dc.subject.MESH | Peptides, Cyclic/chemistry* | - |
dc.title | A cyclic RGD-coated peptide nanoribbon as a selective intracellular nanocarrier | - |
dc.type | Article | - |
dc.contributor.college | Researcher Institutes (부설 연구소) | - |
dc.contributor.department | Institute for Cancer Research (암연구소) | - |
dc.contributor.googleauthor | Yong-beom Lim | - |
dc.contributor.googleauthor | Oh-Joon Kwon | - |
dc.contributor.googleauthor | Eunji Lee | - |
dc.contributor.googleauthor | Pyung-Hwan Kim | - |
dc.contributor.googleauthor | Chae-Ok Yun | - |
dc.contributor.googleauthor | Myongsoo Lee | - |
dc.identifier.doi | 10.1039/b802470g | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00236 | - |
dc.contributor.localId | A01088 | - |
dc.contributor.localId | A02614 | - |
dc.relation.journalcode | J03209 | - |
dc.identifier.eissn | 1477-0539 | - |
dc.identifier.pmid | 18480908 | - |
dc.identifier.url | http://dx.doi.org/10.1039/b802470g | - |
dc.subject.keyword | Amino Acid Sequence | - |
dc.subject.keyword | Circular Dichroism | - |
dc.subject.keyword | HeLa Cells | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Jurkat Cells | - |
dc.subject.keyword | Microscopy, Electron, Transmission | - |
dc.subject.keyword | Molecular Sequence Data | - |
dc.subject.keyword | Nanostructures* | - |
dc.subject.keyword | Oligopeptides/chemistry* | - |
dc.subject.keyword | Peptides, Cyclic/chemistry* | - |
dc.contributor.alternativeName | Kwon, Oh Joon | - |
dc.contributor.alternativeName | Kim, Pyung Hwan | - |
dc.contributor.alternativeName | Yun, Chae Ok | - |
dc.contributor.affiliatedAuthor | Kwon, Oh Joon | - |
dc.contributor.affiliatedAuthor | Kim, Pyung Hwan | - |
dc.contributor.affiliatedAuthor | Yun, Chae Ok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 6 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1944 | - |
dc.citation.endPage | 1948 | - |
dc.identifier.bibliographicCitation | ORGANIC & BIOMOLECULAR CHEMISTRY, Vol.6(11) : 1944-1948, 2008 | - |
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