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Incidence and clinical patterns of polypoidal choroidal vasculopathy in Korean patients

Authors
 Suk Ho Byeon  ;  Sung Chul Lee  ;  Hyun-Sub Oh  ;  Sung Soo Kim  ;  Hyoung Jun Koh  ;  Oh Woong Kwon 
Citation
 JAPANESE JOURNAL OF OPHTHALMOLOGY, Vol.52(1) : 57-62, 2008 
Journal Title
JAPANESE JOURNAL OF OPHTHALMOLOGY
ISSN
 0021-5155 
Issue Date
2008
MeSH
Age Distribution ; Aged ; Aged, 80 and over ; Choroid/blood supply* ; Choroid Diseases/diagnosis ; Choroid Diseases/epidemiology* ; Coloring Agents ; Exudates and Transudates ; Female ; Fluorescein Angiography ; Humans ; Incidence ; Indocyanine Green ; Korea/epidemiology ; Macular Degeneration/diagnosis ; Macular Degeneration/epidemiology ; Male ; Middle Aged ; Peripheral Vascular Diseases/diagnosis ; Peripheral Vascular Diseases/epidemiology* ; Retrospective Studies ; Visual Acuity
Keywords
age-related macular degeneration ; choroidal neovasculopathy ; indocyanine green angiography ; polypoidal choroidal vasculopathy
Abstract
PURPOSE: To determine the incidence, demographic features, and clinical characteristics of polypoidal choroidal vasculopathy (PCV) in Korean patients.

METHODS: A retrospective review was undertaken of 392 eyes of 321 symptomatic patients suspected of having exudative age-related macular degeneration (AMD) after their first visit to a tertiary hospital between February 2002 and May 2006. All patients underwent a complete ophthalmic examination, including fluorescein and indocyanine green angiography (ICGA).

RESULTS: Of the 321 patients (392 eyes), 79 (98 eyes, 24.6%) were diagnosed with PCV. The mean PCV patient age was 64.6 +/- 7.6 years. PCV was more common in men (78.5%), and was usually unilateral (75.9%). In terms of PCV clinical manifestation, 52% of patients showed an exudative pattern, 34.7%, a hemorrhagic pattern, and 13.3%, an extensive hemorrhagic pattern. The mean visual acuity at presentation was 0.231 +/- 0.256. Classification was based on ICGA findings; 52% of patients showed relatively large aneurismal dilations, 25.5% showed atypical vessel deformations, and 22.5% showed dense clusters of numerous small hyperfluorescent dots.

CONCLUSIONS: The incidence of PCV in Korean exudative AMD patients was relatively high compared with that in other ethnic groups. As in other Asian patient populations, PCV occurred more commonly in men and was predominantly unilateral
Full Text
http://link.springer.com/article/10.1007%2Fs10384-007-0498-2
DOI
10.1007/s10384-007-0498-2
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kwon, Oh Woong(권오웅)
Kim, Sung Soo(김성수) ORCID logo https://orcid.org/0000-0002-0574-7993
Byeon, Suk Ho(변석호) ORCID logo https://orcid.org/0000-0001-8101-0830
Oh, Hyun Sub(오현섭)
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106460
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