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Visual prognosis and risk factors for Korean patients with Behcet uveitis

 Young Jae Cho  ;  Wook Kyum Kim  ;  Jong Hyun Lee  ;  Suk Ho Byeon  ;  Hyoung Jun Koh  ;  Oh Woong Kwon  ;  Sung Chul Lee 
 OPHTHALMOLOGICA, Vol.222(5) : 344-350, 2008 
Journal Title
Issue Date
Adolescent ; Adult ; Behcet Syndrome/drug therapy ; Behcet Syndrome/mortality ; Behcet Syndrome/physiopathology* ; Child ; Female ; Follow-Up Studies ; Glucocorticoids/therapeutic use ; Humans ; Kaplan-Meier Estimate ; Korea/epidemiology ; Male ; Middle Aged ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Uveitis/drug therapy ; Uveitis/mortality ; Uveitis/physiopathology* ; Visual Acuity/physiology*
Behcet uveitis ; Visual prognosis ; Visual acuity
PURPOSE: Visual prognosis was evaluated in Korean Behcet uveitis patients. The study investigated factors associated with poor visual outcome, and the effect of various treatments on recurrence-free duration. METHODS: A retrospective analysis was undertaken on 99 consecutive Behcet uveitis patients (168 eyes). Visual prognosis was evaluated using Kaplan-Meier survival curves, and Cox's proportional hazard regression analysis was used to identify risk factors. RESULTS: Visual acuity at the first visit (<0.5), presence of vasculitis, male gender, and posterior/panuveitis type were associated with poor visual prognosis. Visual acuity at the first visit was found to be the most significant risk factor (hazard ratio = 7.392, p = 0.007). Analysis of 9 different treatment modalities showed patients treated with steroids had longer recurrence-free periods than those not treated with steroids (p = 0.0053, t test). CONCLUSION: Whilethe long-term visual prognosis for Behcet uveitis may be affected by many factors, the initial visual acuity appears to be the most significant. Treatments involving steroids appear to decrease the frequency of uveitis recurrence
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kwon, Oh Woong(권오웅)
Byeon, Suk Ho(변석호) ORCID logo https://orcid.org/0000-0001-8101-0830
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
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