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Extent of late gadolinium enhancement in cardiovascular magnetic resonance and its relation with left ventricular diastolic function in patients with hypertrophic cardiomyopathy

DC Field Value Language
dc.contributor.author양우인-
dc.contributor.author임세중-
dc.contributor.author정남식-
dc.contributor.author최대식-
dc.contributor.author최병욱-
dc.contributor.author최의영-
dc.contributor.author하종원-
dc.date.accessioned2015-05-19T16:26:17Z-
dc.date.available2015-05-19T16:26:17Z-
dc.date.issued2008-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106304-
dc.description.abstractBACKGROUND: The aim of this study was to determine whether the extent of late gadolinium enhancement (LGE) is associated with left ventricular (LV) function in patients with hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS: Forty-seven patients with HCM (35 males, mean age 53+/-14, 14 with LV outflow tract obstruction) underwent cardiovascular magnetic resonance imaging and comprehensive echocardiographic examination. The extent of LGE was expressed as LGE volume and LGE percentage of LV volume. LGE was present in 40 (85.1%) of 47 patients. The mean LGE volume was 36.5+/-36 cm3, and the mean percentage of LV volume was 16.4+/-17%. Following adjustment for age, mitral regurgitation and LV mass index, LGE volume and percentage positively correlated with the left atrial volume index (r=0.388, p=0.009 and r=0.425, p=0.004, respectively). However, there was no significant association of functional class, ejection fraction, mitral flow, or annular velocities with the extent of LGE. CONCLUSIONS: In HCM patients, the extent of LGE positively correlated with the left atrial volume index, a surrogate marker of chronic diastolic burden. These findings suggest that myocardial scarring may be a pathologic substrate for chronic diastolic dysfunction in patients with HCM-
dc.description.statementOfResponsibilityopen-
dc.format.extent1449~1453-
dc.relation.isPartOfCIRCULATION JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHCardiomyopathy, Hypertrophic/diagnostic imaging-
dc.subject.MESHCardiomyopathy, Hypertrophic/physiopathology*-
dc.subject.MESHDiastole*-
dc.subject.MESHGadolinium*-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMitral Valve/diagnostic imaging-
dc.subject.MESHMitral Valve/physiopathology-
dc.subject.MESHMitral Valve Insufficiency/diagnostic imaging-
dc.subject.MESHMitral Valve Insufficiency/physiopathology-
dc.subject.MESHRadiography-
dc.subject.MESHStroke Volume*-
dc.subject.MESHVentricular Function, Left*-
dc.titleExtent of late gadolinium enhancement in cardiovascular magnetic resonance and its relation with left ventricular diastolic function in patients with hypertrophic cardiomyopathy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorDae-Sik Choi-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorByoungwook Choi-
dc.contributor.googleauthorWoo-In Yang-
dc.contributor.googleauthorEui-Young Choi-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi18724020-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02301-
dc.contributor.localIdA03372-
dc.contributor.localIdA03585-
dc.contributor.localIdA04048-
dc.contributor.localIdA04059-
dc.contributor.localIdA04165-
dc.contributor.localIdA04257-
dc.relation.journalcodeJ00534-
dc.identifier.eissn1347-4820-
dc.identifier.pmid18724020-
dc.subject.keywordCardiovascular magnetic resonance-
dc.subject.keywordDiastolic function-
dc.subject.keywordHypertrophic cardiomyopathy-
dc.subject.keywordLate gadolinium enhancement-
dc.contributor.alternativeNameYang, Woo In-
dc.contributor.alternativeNameRim, Se Joong-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameChoi, Dae Sik-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.affiliatedAuthorYang, Woo In-
dc.contributor.affiliatedAuthorRim, Se Joong-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorChoi, Dae Sik-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.rights.accessRightsfree-
dc.citation.volume72-
dc.citation.number9-
dc.citation.startPage1449-
dc.citation.endPage1453-
dc.identifier.bibliographicCitationCIRCULATION JOURNAL, Vol.72(9) : 1449-1453, 2008-
dc.identifier.rimsid56340-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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