239 392

Cited 17 times in

Gender-related difference in left ventricular diastolic elastance during exercise in patients with diabetes mellitus.

Authors
 Jong-Won Ha  ;  Hyun-Chul Lee  ;  Sungha Park  ;  Eui-Young Choi  ;  Hye-Sun Seo  ;  Chi-Young Shim  ;  Jin-Mi Kim  ;  Jeong-Ah Ahn  ;  Se-Wha Lee  ;  Se-Joong Rim  ;  Jae K. Oh  ;  Namsik Chung 
Citation
 CIRCULATION JOURNAL, Vol.72(9) : 1443-1448, 2008 
Journal Title
CIRCULATION JOURNAL
ISSN
 1346-9843 
Issue Date
2008
MeSH
Adult ; Aged ; Diabetes Mellitus, Type 2/physiopathology* ; Elasticity ; Exercise* ; Female ; Heart Ventricles/physiopathology* ; Humans ; Male ; Middle Aged ; Mitral Valve/physiopathology* ; Sex Characteristics* ; Sex Factors ; Stroke Volume*
Keywords
Diabetes mellitus ; Diastole ; Exercise ; Gender ; Stiffness
Abstract
BACKGROUND: Because the ratio of mitral inflow and annular velocity to stroke volume has been reported as an index of diastolic elastance (Ed), the hypothesis tested in the present study was that Ed during exercise would be more abnormal in female than in male patients with type 2 diabetes.

METHODS AND RESULTS: Ed was measured at rest and during graded supine bicycle exercise (25W, 3-min increments) in 53 patients (27 males, mean age 53+/-14 years) with type 2 diabetes and 53 age- and gender-matched controls. The patients with diabetes were divided into 2 groups by gender. Ed was not significantly different at rest between men and women, but was significantly higher during exercise in women than in men (25 W, 0.15+/-0.04 vs 0.20+/-0.07, p=0.009; 50 W, 0.16+/-0.05 vs 0.21+/-0.08, p=0.0175).

CONCLUSION: Left ventricular (LV) diastolic elastance is abnormal during exercise, but not at rest, in patients with diabetes without overt heart disease. Female gender was associated with increased LV stiffness during exercise among patients with type 2 diabetes
Files in This Item:
T200800114.pdf Download
DOI
10.1253/circj.CJ-07-1028
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Sung Ha(박성하) ORCID logo https://orcid.org/0000-0001-5362-478X
Seo, Hye Sun(서혜선)
Shim, Chi Young(심지영) ORCID logo https://orcid.org/0000-0002-6136-0136
Lee, Hyun Chul(이현철)
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Chung, Nam Sik(정남식)
Choi, Eui Young(최의영) ORCID logo https://orcid.org/0000-0003-3732-0190
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106241
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links