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Gender-related difference in left ventricular diastolic elastance during exercise in patients with diabetes mellitus.

DC Field Value Language
dc.contributor.author박성하-
dc.contributor.author서혜선-
dc.contributor.author심지영-
dc.contributor.author이현철-
dc.contributor.author임세중-
dc.contributor.author정남식-
dc.contributor.author최의영-
dc.contributor.author하종원-
dc.date.accessioned2015-05-19T16:24:12Z-
dc.date.available2015-05-19T16:24:12Z-
dc.date.issued2008-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106241-
dc.description.abstractBACKGROUND: Because the ratio of mitral inflow and annular velocity to stroke volume has been reported as an index of diastolic elastance (Ed), the hypothesis tested in the present study was that Ed during exercise would be more abnormal in female than in male patients with type 2 diabetes. METHODS AND RESULTS: Ed was measured at rest and during graded supine bicycle exercise (25W, 3-min increments) in 53 patients (27 males, mean age 53+/-14 years) with type 2 diabetes and 53 age- and gender-matched controls. The patients with diabetes were divided into 2 groups by gender. Ed was not significantly different at rest between men and women, but was significantly higher during exercise in women than in men (25 W, 0.15+/-0.04 vs 0.20+/-0.07, p=0.009; 50 W, 0.16+/-0.05 vs 0.21+/-0.08, p=0.0175). CONCLUSION: Left ventricular (LV) diastolic elastance is abnormal during exercise, but not at rest, in patients with diabetes without overt heart disease. Female gender was associated with increased LV stiffness during exercise among patients with type 2 diabetes-
dc.description.statementOfResponsibilityopen-
dc.format.extent1443~1448-
dc.relation.isPartOfCIRCULATION JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHDiabetes Mellitus, Type 2/physiopathology*-
dc.subject.MESHElasticity-
dc.subject.MESHExercise*-
dc.subject.MESHFemale-
dc.subject.MESHHeart Ventricles/physiopathology*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMitral Valve/physiopathology*-
dc.subject.MESHSex Characteristics*-
dc.subject.MESHSex Factors-
dc.subject.MESHStroke Volume*-
dc.titleGender-related difference in left ventricular diastolic elastance during exercise in patients with diabetes mellitus.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorHyun-Chul Lee-
dc.contributor.googleauthorSungha Park-
dc.contributor.googleauthorEui-Young Choi-
dc.contributor.googleauthorHye-Sun Seo-
dc.contributor.googleauthorChi-Young Shim-
dc.contributor.googleauthorJin-Mi Kim-
dc.contributor.googleauthorJeong-Ah Ahn-
dc.contributor.googleauthorSe-Wha Lee-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorJae K. Oh-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1253/circj.CJ-07-1028-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01512-
dc.contributor.localIdA01923-
dc.contributor.localIdA02213-
dc.contributor.localIdA03301-
dc.contributor.localIdA03372-
dc.contributor.localIdA03585-
dc.contributor.localIdA04165-
dc.contributor.localIdA04257-
dc.relation.journalcodeJ00534-
dc.identifier.eissn1347-4820-
dc.identifier.pmid18724019-
dc.subject.keywordDiabetes mellitus-
dc.subject.keywordDiastole-
dc.subject.keywordExercise-
dc.subject.keywordGender-
dc.subject.keywordStiffness-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.alternativeNameSeo, Hye Sun-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameRim, Se Joong-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.affiliatedAuthorPark, Sung Ha-
dc.contributor.affiliatedAuthorSeo, Hye Sun-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorLee, Hyun Chul-
dc.contributor.affiliatedAuthorRim, Se Joong-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.rights.accessRightsfree-
dc.citation.volume72-
dc.citation.number9-
dc.citation.startPage1443-
dc.citation.endPage1448-
dc.identifier.bibliographicCitationCIRCULATION JOURNAL, Vol.72(9) : 1443-1448, 2008-
dc.identifier.rimsid56301-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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