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로타바이러스 백신

Other Titles
 Rotavirus Vaccines 
Authors
 고홍 
Citation
 Korean Journal of Pediatric Gastroenterology and Nutrition (대한소아소화기영양학회지), Vol.12(suppl 1) : 72-76, 2009 
Journal Title
 Korean Journal of Pediatric Gastroenterology and Nutrition (대한소아소화기영양학회지) 
ISSN
 2234-8646 
Issue Date
2009
Keywords
Rotavirus ; Vaccine ; RotaTeqTM ; RotarixTM
Abstract
Rotavirus infection is the leading cause of severe diarrhea disease in infants and young children worldwide. Rotavirus infects every child at least once by her/his 5th birthday. It has been known that single episode of rotavirus infection can protect or alleviate subsequent illness caused by both homotypic and heterotypic rotaviruses. There are two currently licensed rotavirus vaccines. One is human-bovine rotavirus reassortant pentavalent vaccine (RotaTeqTM), which contains five reassortant rotavirus (expressing protein G1, G2, G3, G4 and P[8]) and was licensed in Korea for use among infants in 2007. Another is live-attenuated human rotavirus vaccine (RotarixTM) derived from 89-12 strain which represents the most common of the human rotavirus VP7(G1) and VP4(P[8]) antigens. RotarixTM was licensed in Korea in 2008. Both live oral rotavirus vaccines are efficacious in preventing severe rotavirus gastroenteritis
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hong(고홍) ORCID logo https://orcid.org/0000-0002-3660-7483
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106082
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