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The short-term effects of combined modified constraint-induced movement therapy and botulinum toxin injection for children with spastic hemiplegic cerebral palsy

Authors
 E. S. Park  ;  D.-W. Rha  ;  J. D. Lee  ;  J. K. Yoo  ;  W. H. Chang 
Citation
 NEUROPEDIATRICS, Vol.40(6) : 269-274, 2009 
Journal Title
NEUROPEDIATRICS
ISSN
 0174-304X 
Issue Date
2009
MeSH
Botulinum Toxins, Type A/therapeutic use* ; Cerebral Palsy/complications ; Cerebral Palsy/drug therapy* ; Cerebral Palsy/rehabilitation* ; Child ; Child, Preschool ; Disability Evaluation ; Exercise Therapy/methods* ; Female ; Humans ; Infant ; Male ; Motor Activity/physiology ; Neurologic Examination ; Neuromuscular Agents/therapeutic use* ; Physical Therapy Modalities ; Restraint, Physical/methods* ; Treatment Outcome
Keywords
cerebral palsy ; hemiplegia ; botulinum toxin ; constraint-induced movement therapy ; upper extremity
Abstract
OBJECTIVE: The aim of this study was to investigate whether modified constraint-induced movement therapy (mCIMT) following a botulinum type A toxin (BoNT-A) injection enhances the effects of the BoNT-A injection into the spastic upper limb of children with hemiplegic cerebral palsy (CP).

METHODS: A combined therapy with mCIMT and BoNT-A was given to 17 children in group A. Fifteen children in group B received only the BoNT-A injection. The muscle tone, the movement pattern, and the How Often and the How Well scales in the revised Pediatric Motor Activity Log (revised PMAL) were assessed before and 3 weeks after intervention.

RESULTS: Three participants in group A dropped out due to poor tolerance of mCIMT. There were significant improvements in the muscle tone and the movement patterns for both groups (p<0.05), and the changes were not significantly different between the two groups. The How Often and the How Well scales in the revised PMAL were significantly improved in group A (p<0.05), but not in group B.

CONCLUSION: A combined therapy of mCIMT and BoNT-A seems to be helpful to enhance the effects of the BoNT-A injection in the functional use of the affected limb in children with hemiplegic CP.
Full Text
https://www.thieme-connect.com/DOI/DOI?10.1055/s-0030-1252049
DOI
10.1055/s-0030-1252049
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Rha, Dong Wook(나동욱) ORCID logo https://orcid.org/0000-0002-7153-4937
Park, Eun Sook(박은숙) ORCID logo https://orcid.org/0000-0002-9144-3063
Lee, Jong Doo(이종두)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105884
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