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Clinical features and survival outcomes in patients with multiple myeloma: analysis of web-based data from the Korean Myeloma Registry

Authors
 Seok Jin Kim  ;  Kihyun Kim  ;  Byung Soo Kim  ;  Deog-Yeon Jo  ;  Hye Jin Kang  ;  Jin Seok Kim  ;  Yeung-Chul Mun  ;  Chul Soo Kim  ;  Sang Kyun Sohn  ;  Hyeon-Seok Eom  ;  Jae-Yong Kwak  ;  Hyeok Shim  ;  Hwi-Joong Yoon  ;  Jong-Youl Jin  ;  Chang-Ki Min  ;  Hyunchoon Shin  ;  Jong-Ho Won  ;  Je-Jung Lee  ;  Jung Hye Kwon  ;  Young-Don Joo  ;  Young Rok Do  ;  Sung-Hyun Kim  ;  Sukjoong Oh  ;  Cheolwon Suh  ;  Junglim Lee  ;  Sung-Soo Yoon  ;  Min Kyoung Kim  ;  Soo-Mee Bang  ;  Hun-Mo Ryoo  ;  Bong-Seog Kim  ;  Hawk Kim  ;  Hyo Jung Kim  ;  Yang Soo Kim  ;  Chong Won Park  ;  Gyeong-Won Lee  ;  Ho Jin Shin  ;  Seong Kyu Park  ;  Joon Seong Park  ;  Ho Young Kim  ;  Dong Soon Lee  ;  Jae Hoon Lee 
Citation
 ACTA HAEMATOLOGICA, Vol.122(4) : 200-210, 2009 
Journal Title
 ACTA HAEMATOLOGICA 
ISSN
 0001-5792 
Issue Date
2009
MeSH
Adult ; Aged ; Aged, 80 and over ; Chromosome Aberrations ; Female ; Humans ; Internet ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Multiple Myeloma/diagnosis ; Multiple Myeloma/genetics ; Multiple Myeloma/mortality* ; Multiple Myeloma/therapy ; Prognosis ; Registries/statistics & numerical data ; Republic of Korea/epidemiology ; Stem Cell Transplantation ; Transplantation, Autologous ; Transplantation, Homologous ; Young Adult
Keywords
Multiple myeloma ; Stem cell transplantation ; autologous ; Stem cell transplantation ; tandem autologous
Abstract
AIM: The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system. METHODS: We retrospectively analyzed registered data from 3,209 patients since 1999. RESULTS: The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20-54.06 months). Patients < or =40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT. CONCLUSIONS: We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis.
Full Text
http://www.karger.com/Article/FullText/253027
DOI
10.1159/000253027
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jin Seok(김진석) ORCID logo https://orcid.org/0000-0001-8986-8436
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105713
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