Obesity and liver cancer mortality in Asia: The Asia Pacific Cohort Studies Collaboration
Authors
G. David Batty ; Federica Barzi ; Rachel Huxley ; Charissa Y. Chang ; Sun Ha Jee ; Konrad Jamrozik ; Hyeon Chang Kim ; Xianghua Fang ; Tai H. Lam ; Mark Woodward
Adult ; Aged ; Asia/epidemiology ; Body Mass Index ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Liver Neoplasms/etiology ; Liver Neoplasms/mortality* ; Male ; Middle Aged ; Obesity/complications* ; Risk Factors ; Survival Rate
Keywords
Obesity ; BMI ; Liver cancer
Abstract
While obesity is associated with liver cancer in studies from western societies, the paucity of data from Asia limits insights into its aetiological role in this population. We examined the relationship between body mass index (BMI) and liver cancer mortality using data from the Asia Pacific Cohort Studies Collaboration. In 309,203 Asian study members, 4 years of follow-up gave rise to 11,135 deaths from all causes, 420 of which were ascribed to liver cancer. BMI, whether categorised according to current guidelines for Asian groups or World Health Organisation recommendations, was not associated with liver cancer in any of our analyses.