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Clinical Implications of Serum Retinol-Binding Protein 4 in Asthmatic Children
DC Field | Value | Language |
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dc.contributor.author | 김경원 | - |
dc.contributor.author | 김규언 | - |
dc.contributor.author | 김은수 | - |
dc.contributor.author | 박여훈 | - |
dc.contributor.author | 손명현 | - |
dc.contributor.author | 이경은 | - |
dc.date.accessioned | 2015-04-24T17:34:44Z | - |
dc.date.available | 2015-04-24T17:34:44Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105667 | - |
dc.description.abstract | Recently the prevalence of both asthma and obesity have increased substantially in many countries. The aim of this study was to evaluate the role of retinol-binding protein (RBP) 4 in childhood asthma and its association with atopy markers, pulmonary function, and bronchial hyperresponsiveness in relation to obesity. We studied 160 children between the ages 6 to 10 yr, including 122 asthmatics and 38 controls. The body mass index, pulmonary function tests, and methacholine challenge tests were measured on the same day. Total eosinophil count, serum total IgE, serum eosinophil cationic protein, and serum RBP4 were measured in all subjects. There was no difference in serum RBP4 levels between the asthmatics and the control group. In all subjects or subgroups, serum RBP4 was not associated with total eosinophil count, serum total IgE, serum eosinophil cationic protein, or PC20. There was no relationship between serum RBP4 and pulmonary function in female asthmatics. Forced expiratory volume in 1 second/forced vital capacity (FVC) and forced expiratory flow between 25% and 75% of FVC contributed to serum RBP4 in male asthmatics. Our findings show an association between RBP4 and pulmonary function in prepubertal male asthmatics. This relationship may indirectly affect the high prevalence of childhood asthma in males | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1010~1014 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Asthma*/blood | - |
dc.subject.MESH | Asthma*/immunology | - |
dc.subject.MESH | Bronchial Hyperreactivity/blood | - |
dc.subject.MESH | Bronchial Hyperreactivity/immunology | - |
dc.subject.MESH | Bronchial Provocation Tests | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Obesity/blood | - |
dc.subject.MESH | Obesity/immunology | - |
dc.subject.MESH | Retinol-Binding Proteins, Plasma/metabolism* | - |
dc.title | Clinical Implications of Serum Retinol-Binding Protein 4 in Asthmatic Children | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Medical Research Center (임상의학연구센터) | - |
dc.contributor.googleauthor | Yeo Hoon Park | - |
dc.contributor.googleauthor | Kyung Won Kim | - |
dc.contributor.googleauthor | Kyung Eun Lee | - |
dc.contributor.googleauthor | Eun Soo Kim | - |
dc.contributor.googleauthor | Myung Hyun Sohn | - |
dc.contributor.googleauthor | Kyu-Earn Kim | - |
dc.identifier.doi | 10.3346/jkms.2009.24.6.1010 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00805 | - |
dc.contributor.localId | A02651 | - |
dc.contributor.localId | A00303 | - |
dc.contributor.localId | A00327 | - |
dc.contributor.localId | A01558 | - |
dc.contributor.localId | A01967 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 19949653 | - |
dc.subject.keyword | Asthma | - |
dc.subject.keyword | Child | - |
dc.subject.keyword | Pulmonary Function | - |
dc.subject.keyword | Retinol-Binding Protein 4 | - |
dc.contributor.alternativeName | Kim, Kyung Won | - |
dc.contributor.alternativeName | Kim, Kyu Earn | - |
dc.contributor.alternativeName | Kim, Eun Soo | - |
dc.contributor.alternativeName | Park, Yeo Hoon | - |
dc.contributor.alternativeName | Son, Myung Hyun | - |
dc.contributor.alternativeName | Lee, Kyung Eun | - |
dc.contributor.affiliatedAuthor | Kim, Eun Soo | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Eun | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Won | - |
dc.contributor.affiliatedAuthor | Kim, Kyu Earn | - |
dc.contributor.affiliatedAuthor | Park, Yeo Hoon | - |
dc.contributor.affiliatedAuthor | Son, Myung Hyun | - |
dc.citation.volume | 24 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1010 | - |
dc.citation.endPage | 1014 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.24(6) : 1010-1014, 2009 | - |
dc.identifier.rimsid | 42650 | - |
dc.type.rims | ART | - |
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