Cited 35 times in
Outcome of surgical treatment in non-lesional intractable childhood epilepsy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강훈철 | - |
dc.contributor.author | 김동석 | - |
dc.contributor.author | 김세훈 | - |
dc.contributor.author | 김태승 | - |
dc.contributor.author | 김흥동 | - |
dc.contributor.author | 이승구 | - |
dc.contributor.author | 이준수 | - |
dc.date.accessioned | 2015-04-24T17:16:46Z | - |
dc.date.available | 2015-04-24T17:16:46Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1059-1311 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105096 | - |
dc.description.abstract | PURPOSE: The aim of this study is to investigate seizure outcomes following epilepsy surgery in non-lesional neocortical pediatric epilepsy. METHODS: We performed a retrospective study on 27 patients with intractable childhood epilepsy who received epilepsy surgery between 1999 and 2006 at Sang-gye Paik Hospital and Severance Children's Hospital. None of the patients had any detectable lesions on MRI. Surgical outcome was assessed at least 2 years postoperatively; clinical characteristics, surgical outcome, pathologic findings, types of surgery, localizing features on SPECT, FDG-PET, and long-term video-EEG were reviewed. RESULTS: Eighteen patients (67%) demonstrated an Engel class I outcome postoperatively. The mean follow-up duration was 4.3 years (range, 2.2-9 years). Eighteen out of 27 cases (67%) showed focal localizing features on ictal SPECT, and 21 of 27 cases (78%) showed abnormal findings on PET. Single lobectomy was the most common procedure, and was performed in 20 patients (74%). Multilobar resection was performed in seven patients (26%). Cortical dysplasia was the most common finding during pathological examination, and was observed in 15 (56%) cases. In addition, gliosis was found in two patients (7%) and non-specific pathological findings were described in 10 patients (37%). CONCLUSIONS: In children with intractable epilepsy and a MRI demonstrating no abnormal lesions, epileptic surgery should be strongly considered when cortical pathology can be identified from other studies | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 625~629 | - |
dc.relation.isPartOf | SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Epilepsy/diagnostic imaging | - |
dc.subject.MESH | Epilepsy/pathology | - |
dc.subject.MESH | Epilepsy/surgery* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neurosurgical Procedures* | - |
dc.subject.MESH | Positron-Emission Tomography | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Tomography, Emission-Computed, Single-Photon | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Outcome of surgical treatment in non-lesional intractable childhood epilepsy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Joo Hee Seo | - |
dc.contributor.googleauthor | Byoung Ho Noh | - |
dc.contributor.googleauthor | Joon Soo Lee | - |
dc.contributor.googleauthor | Dong Suk Kim | - |
dc.contributor.googleauthor | Seung Koo Lee | - |
dc.contributor.googleauthor | Tae Seung Kim | - |
dc.contributor.googleauthor | Se Hoon Kim | - |
dc.contributor.googleauthor | Hoon Chul Kang | - |
dc.contributor.googleauthor | Heung Dong Kim | - |
dc.identifier.doi | 10.1016/j.seizure.2009.07.007 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00102 | - |
dc.contributor.localId | A00402 | - |
dc.contributor.localId | A00610 | - |
dc.contributor.localId | A01071 | - |
dc.contributor.localId | A01208 | - |
dc.contributor.localId | A02912 | - |
dc.contributor.localId | A03177 | - |
dc.relation.journalcode | J02648 | - |
dc.identifier.eissn | 1532-2688 | - |
dc.identifier.pmid | 19683462 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1059131109001411 | - |
dc.subject.keyword | Intractable childhood epilepsy | - |
dc.subject.keyword | Epilepsy surgery | - |
dc.subject.keyword | Normal magnetic resonance imaging | - |
dc.subject.keyword | Surgical outcome | - |
dc.contributor.alternativeName | Kang, Hoon Chul | - |
dc.contributor.alternativeName | Kim, Dong Seok | - |
dc.contributor.alternativeName | Kim, Se Hoon | - |
dc.contributor.alternativeName | Kim, Tai Seung | - |
dc.contributor.alternativeName | Kim, Heung Dong | - |
dc.contributor.alternativeName | Lee, Seung Koo | - |
dc.contributor.alternativeName | Lee, Joon Soo | - |
dc.contributor.affiliatedAuthor | Kang, Hoon Chul | - |
dc.contributor.affiliatedAuthor | Kim, Dong Seok | - |
dc.contributor.affiliatedAuthor | Kim, Se Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Tai Seung | - |
dc.contributor.affiliatedAuthor | Kim, Heung Dong | - |
dc.contributor.affiliatedAuthor | Lee, Seung Koo | - |
dc.contributor.affiliatedAuthor | Lee, Joon Soo | - |
dc.citation.volume | 18 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 625 | - |
dc.citation.endPage | 629 | - |
dc.identifier.bibliographicCitation | SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, Vol.18(9) : 625-629, 2009 | - |
dc.identifier.rimsid | 56742 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.