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Outcome of surgical treatment in non-lesional intractable childhood epilepsy

DC Field Value Language
dc.contributor.author강훈철-
dc.contributor.author김동석-
dc.contributor.author김세훈-
dc.contributor.author김태승-
dc.contributor.author김흥동-
dc.contributor.author이승구-
dc.contributor.author이준수-
dc.date.accessioned2015-04-24T17:16:46Z-
dc.date.available2015-04-24T17:16:46Z-
dc.date.issued2009-
dc.identifier.issn1059-1311-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/105096-
dc.description.abstractPURPOSE: The aim of this study is to investigate seizure outcomes following epilepsy surgery in non-lesional neocortical pediatric epilepsy. METHODS: We performed a retrospective study on 27 patients with intractable childhood epilepsy who received epilepsy surgery between 1999 and 2006 at Sang-gye Paik Hospital and Severance Children's Hospital. None of the patients had any detectable lesions on MRI. Surgical outcome was assessed at least 2 years postoperatively; clinical characteristics, surgical outcome, pathologic findings, types of surgery, localizing features on SPECT, FDG-PET, and long-term video-EEG were reviewed. RESULTS: Eighteen patients (67%) demonstrated an Engel class I outcome postoperatively. The mean follow-up duration was 4.3 years (range, 2.2-9 years). Eighteen out of 27 cases (67%) showed focal localizing features on ictal SPECT, and 21 of 27 cases (78%) showed abnormal findings on PET. Single lobectomy was the most common procedure, and was performed in 20 patients (74%). Multilobar resection was performed in seven patients (26%). Cortical dysplasia was the most common finding during pathological examination, and was observed in 15 (56%) cases. In addition, gliosis was found in two patients (7%) and non-specific pathological findings were described in 10 patients (37%). CONCLUSIONS: In children with intractable epilepsy and a MRI demonstrating no abnormal lesions, epileptic surgery should be strongly considered when cortical pathology can be identified from other studies-
dc.description.statementOfResponsibilityopen-
dc.format.extent625~629-
dc.relation.isPartOfSEIZURE-EUROPEAN JOURNAL OF EPILEPSY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHEpilepsy/diagnostic imaging-
dc.subject.MESHEpilepsy/pathology-
dc.subject.MESHEpilepsy/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMale-
dc.subject.MESHNeurosurgical Procedures*-
dc.subject.MESHPositron-Emission Tomography-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTomography, Emission-Computed, Single-Photon-
dc.subject.MESHTreatment Outcome-
dc.titleOutcome of surgical treatment in non-lesional intractable childhood epilepsy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorJoo Hee Seo-
dc.contributor.googleauthorByoung Ho Noh-
dc.contributor.googleauthorJoon Soo Lee-
dc.contributor.googleauthorDong Suk Kim-
dc.contributor.googleauthorSeung Koo Lee-
dc.contributor.googleauthorTae Seung Kim-
dc.contributor.googleauthorSe Hoon Kim-
dc.contributor.googleauthorHoon Chul Kang-
dc.contributor.googleauthorHeung Dong Kim-
dc.identifier.doi10.1016/j.seizure.2009.07.007-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00102-
dc.contributor.localIdA00402-
dc.contributor.localIdA00610-
dc.contributor.localIdA01071-
dc.contributor.localIdA01208-
dc.contributor.localIdA02912-
dc.contributor.localIdA03177-
dc.relation.journalcodeJ02648-
dc.identifier.eissn1532-2688-
dc.identifier.pmid19683462-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1059131109001411-
dc.subject.keywordIntractable childhood epilepsy-
dc.subject.keywordEpilepsy surgery-
dc.subject.keywordNormal magnetic resonance imaging-
dc.subject.keywordSurgical outcome-
dc.contributor.alternativeNameKang, Hoon Chul-
dc.contributor.alternativeNameKim, Dong Seok-
dc.contributor.alternativeNameKim, Se Hoon-
dc.contributor.alternativeNameKim, Tai Seung-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameLee, Seung Koo-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthorKang, Hoon Chul-
dc.contributor.affiliatedAuthorKim, Dong Seok-
dc.contributor.affiliatedAuthorKim, Se Hoon-
dc.contributor.affiliatedAuthorKim, Tai Seung-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorLee, Seung Koo-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.citation.volume18-
dc.citation.number9-
dc.citation.startPage625-
dc.citation.endPage629-
dc.identifier.bibliographicCitationSEIZURE-EUROPEAN JOURNAL OF EPILEPSY, Vol.18(9) : 625-629, 2009-
dc.identifier.rimsid56742-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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