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Synthesis of gold nanorod-embedded polymeric nanoparticles by a nanoprecipitation method for use as photothermal agents

DC Field Value Language
dc.contributor.author서진석-
dc.contributor.author양재문-
dc.contributor.author허용민-
dc.date.accessioned2015-04-24T16:56:29Z-
dc.date.available2015-04-24T16:56:29Z-
dc.date.issued2009-
dc.identifier.issn0957-4484-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104459-
dc.description.abstractFor the synthesis of biocompatible photothermal agents, gold nanorod-embedded polymeric nanoparticles (GPNs) were synthesized using a nanoprecipitation method. Uniform gold nanorods (GNRs), which are sensitive to a photothermal effect by near-infrared (NIR) light, with an aspect ratio of 4.0 were synthesized by a seed-mediated growth method. The hydroxyl groups of polycaprolactone diol (PCL diOH) were modified by esterification with mercaptopropionic acid to give a dithiol (polycaprolactone dithiol, PCL diSH) as a phase transfer and capping agent. Subsequently, hexadecyltrimethylammonium bromide (CTAB), a stabilizer of GNRs, was exchanged and/or removed by PCL diSH. PCL diSH-coated GNRs were further wrapped in a hydrophilic polymer, Pluronic F127, as a stabilizer. These newly formulated GPNs exhibit excellent stability in water and a maximum absorbance in the NIR region indicating a highly efficient surface plasmon resonance effect, phenomena useful for photothermal agents-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfNANOTECHNOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBiocompatible Materials/chemistry-
dc.subject.MESHChemical Precipitation-
dc.subject.MESHGold/chemistry*-
dc.subject.MESHMetal Nanoparticles/chemistry*-
dc.subject.MESHMicroscopy, Electron, Transmission-
dc.subject.MESHNanotechnology/methods*-
dc.subject.MESHPhotochemical Processes-
dc.subject.MESHPolyesters/chemistry*-
dc.subject.MESHSpectroscopy, Fourier Transform Infrared-
dc.subject.MESHSpectroscopy, Near-Infrared-
dc.subject.MESHTemperature-
dc.titleSynthesis of gold nanorod-embedded polymeric nanoparticles by a nanoprecipitation method for use as photothermal agents-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorEunjung Kim-
dc.contributor.googleauthorJaemoon Yang-
dc.contributor.googleauthorJihye Choi-
dc.contributor.googleauthorJin-Suck Suh-
dc.contributor.googleauthorYong-Min Huh-
dc.contributor.googleauthorSeungjoo Haam-
dc.identifier.doi10.1088/0957-4484/20/36/365602-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02315-
dc.contributor.localIdA01916-
dc.contributor.localIdA04359-
dc.relation.journalcodeJ02287-
dc.identifier.eissn1361-6528-
dc.identifier.pmid19687560-
dc.identifier.urlhttp://iopscience.iop.org/0957-4484/20/36/365602/-
dc.contributor.alternativeNameSuh, Jin Suck-
dc.contributor.alternativeNameYang, Jae Moon-
dc.contributor.alternativeNameHuh, Yong Min-
dc.contributor.affiliatedAuthorYang, Jae Moon-
dc.contributor.affiliatedAuthorSuh, Jin Suck-
dc.contributor.affiliatedAuthorHuh, Yong Min-
dc.citation.volume20-
dc.citation.number36-
dc.citation.startPage365602-
dc.identifier.bibliographicCitationNANOTECHNOLOGY, Vol.20(36) : 365602, 2009-
dc.identifier.rimsid54133-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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