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Pulmonary aspergilloma: analysis of prognosis in relation to symptoms and treatment

 Jin Gu Lee  ;  Chang Young Lee  ;  In Kyu Park  ;  Dae Joon Kim  ;  Joon Chang  ;  Se Kyu Kim  ;  Kyung Young Chung 
 Journal of Thoracic and Cardiovascular Surgery, Vol.138(4) : 820-825, 2009 
Journal Title
 Journal of Thoracic and Cardiovascular Surgery 
Issue Date
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aspergillosis/complications ; Aspergillosis/diagnosis ; Aspergillosis/surgery* ; Child ; Female ; Humans ; Lung Diseases, Fungal/complications ; Lung Diseases, Fungal/diagnosis ; Lung Diseases, Fungal/surgery* ; Male ; Middle Aged ; Postoperative Complications ; Prognosis ; Young Adult
BACKGROUND: This study was conducted to assess the risk of surgical treatment and to evaluate surgical resection in patients with pulmonary aspergilloma. METHOD: We reviewed 240 patients with pulmonary aspergilloma who were diagnosed between 1990 and 2006. Of these, 135 patients underwent surgical procedure (group A) and 105 patients were managed with conservative treatment (group B). RESULT: Forty complications (29.6%) and 6 operative mortalities (4.4%) developed in group A. During the follow-up period, there were 5 recurrences (3.9%) after surgical procedure. The overall 10-year survival rates of group A and group B were 84.8% and 56.7% (P < .001). In multivariate analysis, age, sex, and surgical treatment were favorable prognostic factors. Symptoms of hemoptysis and blood-tinged sputum were not significant prognostic factor even in univariate analysis. CONCLUSION: Our results indicate that (1) early morbidity and mortality rates of surgical treatment for pulmonary aspergilloma are acceptable, and (2) surgical treatment is helpful not only to reduce symptoms but also to prolong the survival of patients with pulmonary aspergilloma. Although more studies are needed, our data support the conclusion that surgical resection should be considered for all patients with pulmonary aspergilloma who have acceptable pulmonary reserve
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dae Joon(김대준)
Kim, Se Kyu(김세규)
Park, In Kyu(박인규)
Lee, Jin Gu(이진구)
Lee, Chang Young(이창영)
Chang, Joon(장준) ORCID logo https://orcid.org/0000-0003-4542-6841
Chung, Kyung Young(정경영)
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