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TDM 및 남용약물검사 신빙도검사 결과보고 (2008)

Other Titles
 Annual Report on 2008 External Quality Assessment in Therapeutic Drug Monitoring and Drug of Abuse in Korea(2008) 
Authors
 김정호  ;  김병광  ;  이수연  ;  신동훈  ;  송경은  ;  윤여민  ;  서순팔  ;  송선미  ;  전사일  ;  권계철  ;  김진규  ;  이운형 
Citation
 Journal of Laboratory Medicine and Quality Assurance (임상검사와 정도관리), Vol.31(1) : 125-142, 2009 
Journal Title
Journal of Laboratory Medicine and Quality Assurance(임상검사와 정도관리)
ISSN
 1225-097X 
Issue Date
2009
Abstract
Two trials of external quality assessment for Therapeutic Drug Monitoring (TDM) subcommittee of Korean Association of Quality Assurance for Clinical Laboratory (KAQACL) were performed in 2008. The number of participating laboratories were 114, which is similar with that of the previous year. Average response rates were 97.8% in both trials slightly lower than that of the previous year. Two kinds of control materials were requested to be tested in each trial so that each laboratory could know the possible systematic error. The average drug item was 6.3 per laboratory, which was decreased slightly from 6.8 in recent 5 years, and the maximum was 18 items. The most common test items were valproic acid, digoxin, carbamazepine, theophylline, phenytoin, and phenobarbital which were peformed in more than 52.1% of participating laboratories, followed by cyclosporine, vancomycin, tacrolimus, lithium, methotrexate, amikacin, tobramycin, gentamycin, acetaminophen, salicylate, free phenytoin, primidone, and amitryptyline. The widely used TDM analyzers were Abbott TDx/TDxFLx (35.3%), followed by Abbott AxSym (26.5%) and Roche Cobas Integra (17.3%), Abbott IMx (3.3%), and Siemens Viva E (3.0%). The inter-laboratory coefficients of variations showed similar tendency comparing with those of the previous years. The number of participating laboratories for drug of abuse tests were 17, which is similar to that of the previous year. Average drug item were 3.7 for the 1st trial. We found the relatively good performance as we got the correct answers for all laboratories except 2 laboratories. In conclusion, the TDM external quality assessment of 2008 showed grossly similar pattern comparing with that of previous year.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jeong Ho(김정호) ORCID logo https://orcid.org/0000-0003-2479-0548
Lee, Woon Hyoung(이운형)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104291
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