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Clinical experience of single-session percutaneous aspiration and OK-432 sclerotherapy for treatment of simple renal cysts: 1-year follow-up

 Young Deuk Choi  ;  Won Sik Ham  ;  Won Tae Kim  ;  Kang Su Cho  ;  Joo Hyoung Lee  ;  Soung Yong Cho  ;  Ju Wan Seo  ;  Ok Hyun Jin 
 JOURNAL OF ENDOUROLOGY, Vol.23(6) : 1001-1006, 2009 
Journal Title
Issue Date
Aged ; Biopsy, Needle ; Female ; Follow-Up Studies ; Humans ; Kidney Diseases, Cystic/diagnostic imaging ; Kidney Diseases, Cystic/pathology* ; Kidney Diseases, Cystic/therapy* ; Male ; Middle Aged ; Picibanil/therapeutic use* ; Sclerosing Solutions/therapeutic use ; Sclerotherapy/adverse effects ; Sclerotherapy/methods* ; Tomography, X-Ray Computed ; Treatment Outcome
PURPOSE: To evaluate the efficacy and safety of single-session OK-432 sclerotherapy for the treatment of renal cysts.

MATERIALS AND METHODS: From October 2005 to November 2006, 48 patients (61 simple renal cysts) were included in the study. Indications were determined as flank discomfort (n = 37) or patient reassurance due to increasing size (n = 11). The simple renal cysts were aspirated under ultrasonography (US), at which point OK-432 was injected into the cyst. Follow-up was performed with US or computed tomography scan every 3 months until 1 year. Complete regression of the renal cyst or more than 70% reduction in size with no symptoms indicated a successful treatment.

RESULTS: Among 61 renal cysts of 48 patients, the overall success rate was 98.4%. Complete regression occurred in 46 cysts (75.4%), and more than 90% reduction in size occurred in 6 cysts (9.8%). A size reduction of 80% to 90% and 70% to 80% occurred in five (8.2%) and three cysts (4.9%), respectively. A size reduction less than 70% occurred in only one cyst (1.6%). The success of cyst regression was correlated with cyst volume. Clinical symptoms resolved in 100% of patients with symptomatic cysts, and there was no enlargement of the aspirated cysts at the 1-year follow-up. After the procedure, there were only some minor complications, such as mild fever, flank pain, and leukocytosis, which subsided with the conservative treatment.

CONCLUSIONS: Percutaneous OK-432 sclerotherapy is simple, safe, and effective, and it can be an alternative first-line therapy for simple renal cysts.
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1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Won Tae(김원태)
Cho, Kang Su(조강수) ORCID logo https://orcid.org/0000-0002-3500-8833
Cho, Soung Yong(조성용)
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
Ham, Won Sik(함원식) ORCID logo https://orcid.org/0000-0003-2246-8838
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