Cited 25 times in
Considerations for implantation site of VX2 carcinoma into rabbit liver.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이광훈 | - |
dc.date.accessioned | 2015-04-24T16:40:00Z | - |
dc.date.available | 2015-04-24T16:40:00Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1051-0443 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103943 | - |
dc.description.abstract | PURPOSE: To assess whether the implantation site of VX2 carcinoma into rabbit liver affects successful vessel selection for transcatheter arterial interventions. MATERIALS AND METHODS: Twenty-four New Zealand White rabbits were randomly assigned to two groups. All implantations were performed by open laparotomy with minced tumor cells inserted into a 16-gauge Angiocath needle. Group I rabbits (n = 12) had tumor implanted into the left medial lobe of the liver and group II rabbits (n = 12) had tumor implanted into the left lateral lobe. Two weeks after implantation, selective angiography was performed for subsequent chemoembolization, which was part of a different study. Tested variables included maximum tumor diameter, tumor feeding artery size, and tumor vascularity. RESULTS: Successful tumor growth was achieved in all rabbits. Selective angiography was possible in 33.3% of rabbits in group I and 66.6% of rabbits in group II (P < .05). Tumor size and vascularity were similar between groups. Mean lengths of tumor feeder arteries from the bifurcation of the left hepatic artery were 4.1 mm +/- 1.2 in group I (left medial lobe) and 10.8 mm +/- 3.0 in group II (left lateral lobe; P < .05). The angulation of the left medial lobar artery (group I) off the left hepatic artery was acute in eight of 12 rabbits (66.6%), but only four of 12 rabbits in group II (33.3%) showed acute angulation of the left lateral lobar artery off the left hepatic artery (P < .05). Mean angiography time was significantly shorter in group II. CONCLUSIONS: For selective hepatic arterial interventions, the left lateral lobe of the liver may be favorable as an implantation site for VX2 tumors in rabbits. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 113~117 | - |
dc.relation.isPartOf | JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Angiography, Digital Subtraction | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Carcinoma/blood supply* | - |
dc.subject.MESH | Carcinoma/diagnostic imaging | - |
dc.subject.MESH | Carcinoma/pathology | - |
dc.subject.MESH | Carcinoma/therapy | - |
dc.subject.MESH | Chemoembolization, Therapeutic* | - |
dc.subject.MESH | Hepatic Artery*/diagnostic imaging | - |
dc.subject.MESH | Injections | - |
dc.subject.MESH | Liver Neoplasms, Experimental/blood supply* | - |
dc.subject.MESH | Liver Neoplasms, Experimental/diagnostic imaging | - |
dc.subject.MESH | Liver Neoplasms, Experimental/pathology | - |
dc.subject.MESH | Liver Neoplasms, Experimental/therapy | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neoplasm Transplantation | - |
dc.subject.MESH | Neovascularization, Pathologic/diagnostic imaging | - |
dc.subject.MESH | Rabbits | - |
dc.title | Considerations for implantation site of VX2 carcinoma into rabbit liver. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Kwang-Hun Lee | - |
dc.contributor.googleauthor | Eleni Liapi | - |
dc.contributor.googleauthor | Manon Buijs | - |
dc.contributor.googleauthor | Josephina Vossen | - |
dc.contributor.googleauthor | Kelvin Hong | - |
dc.contributor.googleauthor | Christos Georgiades | - |
dc.contributor.googleauthor | Jean-Francois H. Geschwind | - |
dc.identifier.doi | 10.1016/j.jvir.2008.09.033 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02676 | - |
dc.relation.journalcode | J01922 | - |
dc.identifier.eissn | 1535-7732 | - |
dc.identifier.pmid | 19028118 | - |
dc.contributor.alternativeName | Lee, Kwang Hun | - |
dc.contributor.affiliatedAuthor | Lee, Kwang Hun | - |
dc.citation.volume | 20 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 113 | - |
dc.citation.endPage | 117 | - |
dc.identifier.bibliographicCitation | JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, Vol.20(1) : 113-117, 2009 | - |
dc.identifier.rimsid | 37901 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.