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Early surgery of hamartoma of the floor of the fourth ventricle: a case report.

Authors
 Young Seok Park  ;  Min-Chul Oh  ;  Heung Dong Kim  ;  Dong-Seok Kim 
Citation
 BRAIN & DEVELOPMENT, Vol.31(5) : 347-351, 2009 
Journal Title
 BRAIN & DEVELOPMENT 
ISSN
 0387-7604 
Issue Date
2009
MeSH
Age of Onset ; Cerebellum/pathology ; Cerebral Ventricle Neoplasms/complications ; Cerebral Ventricle Neoplasms/pathology* ; Cerebral Ventricle Neoplasms/surgery* ; Early Diagnosis ; Epilepsy/etiology* ; Fourth Ventricle/pathology* ; Fourth Ventricle/physiopathology ; Fourth Ventricle/surgery* ; Hamartoma/complications ; Hamartoma/pathology* ; Hamartoma/surgery* ; Hemifacial Spasm/etiology ; Humans ; Infant ; Intraoperative Complications/etiology ; Intraoperative Complications/physiopathology ; Magnetic Resonance Imaging ; Male ; Neurosurgical Procedures ; Patient Selection ; Preoperative Care/methods ; Prognosis ; Reoperation ; Treatment Outcome
Keywords
Hamartoma ; Status epilepticus ; Hemifacial spasm ; Fourth ventricle ; Cerebellar neoplasm
Abstract
Epilepsy from hamartoma of the floor of fourth ventricle (HFFV) is very rare, starting in neonate or infantile period, good response to surgery. We report a 3-month-old boy with episodes of medically intractable abnormal eyelid blinking and hemifacial seizure. The episodes began from the first day of life and were unresponsive to medication. A magnetic resonance imaging scan revealed mass lesion on the floor of fourth ventricle, with extended cerebellar peduncle and cerebellar hemisphere. Surgery had been performed two times previously for treatment; only a subtotal resection was performed due to severe bradycardia during the first operation. The patient underwent second operation for gross total removal of tumor. Complete resection of the mass after second surgery resulted in remission of seizures and histopathology revealed hamartoma with hemangiomatous vessel proliferation. Identification of characteristic semiology and associated HFFV can help prediction of intractability even in infant and favoring surgical treatment in early age. To our knowledge, this is the youngest patient who underwent early surgery just after progressing into status for HFFV, showing complete lesion resection resulting in successful seizure outcome
Full Text
http://www.sciencedirect.com/science/article/pii/S0387760408000909
DOI
10.1016/j.braindev.2008.03.013
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Seok(김동석)
Kim, Heung Dong(김흥동) ORCID logo https://orcid.org/0000-0002-8031-7336
Park, Young Seok(박영석)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/103658
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