172 232

Cited 27 times in

Pulmonary atresia with ventricular septal defects and major aortopulmonary collateral arteries.

 Suk-Won Song  ;  Han Ki Park  ;  Young-Hwan Park  ;  Bum Koo Cho 
 CIRCULATION JOURNAL, Vol.73(3) : 516-522, 2009 
Journal Title
Issue Date
Adolescent ; Aorta, Thoracic/abnormalities* ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Child ; Child, Preschool ; Collateral Circulation ; Coronary Angiography ; Coronary Circulation ; Female ; Follow-Up Studies ; Heart Septal Defects, Ventricular/diagnostic imaging ; Heart Septal Defects, Ventricular/mortality* ; Heart Septal Defects, Ventricular/surgery* ; Humans ; Infant ; Infant, Newborn ; Kaplan-Meier Estimate ; Male ; Pulmonary Artery/abnormalities* ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/surgery ; Pulmonary Atresia/diagnostic imaging ; Pulmonary Atresia/mortality* ; Pulmonary Atresia/surgery* ; Reoperation/statistics & numerical data ; Risk Factors
Collateral blood flow ; Congenital heart disease ; Cyanosis
BACKGROUND: There is no consensus on the long-term outcome after unifocalization in patients undergoing surgery for pulmonary atresia with ventricular septal defects (VSD) and major aortopulmonary collateral arteries (MAPCAs). METHODS AND RESULTS: From 1988 to 2006, 40 patients (median age 8.5 months) underwent surgery for pulmonary atresia, VSD, and MAPCAs. The hospital mortality rate for the preparatory procedures was 1.2%; 17 patients had a complete repair (CR) at a median age of 3 years. Patients with a pulmonary artery index greater than 100 mm(2)/m(2) had a higher likelihood of CR. The overall survival rate 15 years after first operation in the CR group was 87.5%. Cox analysis demonstrated that increased number of MAPCAs (P=0.019, HR=1.666) was a significant predictor of poor survival, and CR (P=0.025, HR=0.141) was a significant predictor of favorable prognosis. On angiography, serial measurements of MAPCAs showed a significant decrease in size (from 5.2+/-2.9 to 4.1+/-2.9 mm after a mean of 20 months) (P<0.0001). CONCLUSIONS: Long-term survival into adulthood can be achieved with an integrated approach. Late survival depends on the number of MAPCAs, and CR. Growth potential of unifocalized MAPCAs was not definite.
Files in This Item:
T200900657.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Park, Young Hwan(박영환)
Park, Han Ki(박한기) ORCID logo https://orcid.org/0000-0002-7472-7822
Song, Suk Won(송석원) ORCID logo https://orcid.org/0000-0002-9850-9707
Cho, Bum Koo(조범구)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.