Cited 155 times in
Can microvessel invasion of hepatocellular carcinoma be predicted by pre-operative MRI?
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박미숙 | - |
dc.contributor.author | 박영년 | - |
dc.contributor.author | 최진섭 | - |
dc.contributor.author | 최진영 | - |
dc.contributor.author | 한광협 | - |
dc.contributor.author | 김경식 | - |
dc.contributor.author | 김기황 | - |
dc.contributor.author | 김명진 | - |
dc.date.accessioned | 2015-04-24T16:28:29Z | - |
dc.date.available | 2015-04-24T16:28:29Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103580 | - |
dc.description.abstract | Microvessel invasion is a major prognostic factor in hepatocellular carcinoma (HCC) that influences the suitability of surgery, but rarely can be evaluated preoperatively. This study was performed to identify preoperative MRI findings that reflect histopathological microvessel invasion in hepatocellular carcinoma. Gadobenate dimeglumine-enhanced four-arterial phase dynamic study and hepatobiliary phase images of preoperative MRI of 70 HCC lesions were retrospectively reviewed. Tumor size (cm), peritumoral enhancement, tumor margins, and radiological capsule were analyzed as radiological parameters reflecting microvessel invasion and were compared with histopathological references. The chi-square test and the independent t-test were used for univariate analysis, and a logistic regression analysis was performed for multivariate analysis. In univariate analysis, tumor size (p = 0.030), peritumoral enhancement (p < 0.001), and tumor margins (p = 0.007) were associated with microvessel tumor invasion. However, in multivariate analysis irregular circumferential peritumoral enhancement only showed statistical significance (odds ratio 13.0), suggesting a high probability of microvessel invasion of HCC. Irregular circumferential peritumoral enhancement on contrast-enhanced multi-arterial phase dynamic MRI could be a preoperative surrogate marker for microvessel tumor invasion. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1744~1751 | - |
dc.relation.isPartOf | EUROPEAN RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carcinoma, Hepatocellular/pathology* | - |
dc.subject.MESH | Carcinoma, Hepatocellular/surgery | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Neoplasms/pathology* | - |
dc.subject.MESH | Liver Neoplasms/surgery | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Microvessels/pathology* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Invasiveness | - |
dc.subject.MESH | Neovascularization, Pathologic/pathology* | - |
dc.subject.MESH | Neovascularization, Pathologic/surgery | - |
dc.subject.MESH | Preoperative Care/methods | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Can microvessel invasion of hepatocellular carcinoma be predicted by pre-operative MRI? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Honsoul Kim | - |
dc.contributor.googleauthor | Mi-Suk Park | - |
dc.contributor.googleauthor | Jin Young Choi | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Kyung Sik Kim | - |
dc.contributor.googleauthor | Jin Sub Choi | - |
dc.contributor.googleauthor | Kwang-Hyub Han | - |
dc.contributor.googleauthor | EunJu Kim | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.identifier.doi | 10.1007/s00330-009-1331-8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01463 | - |
dc.contributor.localId | A01563 | - |
dc.contributor.localId | A04199 | - |
dc.contributor.localId | A04200 | - |
dc.contributor.localId | A04268 | - |
dc.contributor.localId | A00299 | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A00426 | - |
dc.relation.journalcode | J00851 | - |
dc.identifier.eissn | 1432-1084 | - |
dc.identifier.pmid | 19247666 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00330-009-1331-8 | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.subject.keyword | Microvessel tumor invasion | - |
dc.subject.keyword | Peritumoral enhancement | - |
dc.subject.keyword | MRI | - |
dc.contributor.alternativeName | Park, Mi Sook | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.alternativeName | Choi, Jin Sub | - |
dc.contributor.alternativeName | Choi, Jin Young | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.alternativeName | Kim, Kyung Sik | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Park, Mi-Suk | - |
dc.contributor.affiliatedAuthor | Park, Young Nyun | - |
dc.contributor.affiliatedAuthor | Choi, Jin Sub | - |
dc.contributor.affiliatedAuthor | Choi, Jin Young | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Sik | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.citation.volume | 19 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1744 | - |
dc.citation.endPage | 1751 | - |
dc.identifier.bibliographicCitation | EUROPEAN RADIOLOGY, Vol.19(7) : 1744-1751, 2009 | - |
dc.identifier.rimsid | 37935 | - |
dc.type.rims | ART | - |
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