Cited 41 times in
Elevated white blood cell count is associated with arterial stiffness
DC Field | Value | Language |
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dc.contributor.author | 이용제 | - |
dc.contributor.author | 이정현 | - |
dc.contributor.author | 이지원 | - |
dc.contributor.author | 이혜리 | - |
dc.contributor.author | 김종구 | - |
dc.contributor.author | 심재용 | - |
dc.contributor.author | 이덕철 | - |
dc.date.accessioned | 2015-04-24T16:24:15Z | - |
dc.date.available | 2015-04-24T16:24:15Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0939-4753 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103450 | - |
dc.description.abstract | BACKGROUND AND AIMS: White blood cell (WBC) count, a usual marker of systemic inflammation, is known to be associated with atherosclerotic cardiovascular disease. The aim of the present study was to determine the association of WBC count with arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV). METHODS AND RESULTS: We examined the association between WBC count and baPWV in 788 Korean adults (375 men, 413 women) in a health examination program. The odds ratios for a high baPWV were calculated using multivariate logistic regression analysis after adjusting for confounding variables across WBC count quartiles (Q1: <or=5190, Q2: 5200-6080, Q3: 6090-7310, and Q4: >or=7320 cells/mm(3)). A high baPWV was defined as more than 1440 cm/s (>75th percentile). Age-adjusted baPWV mean values gradually increased with WBC quartiles (Q1=1294, Q2=1322, Q3=1347, and Q4=1367 cm/s). The odds ratios (95% CI) for a high baPWV in each WBC count quartile were 1.00, 1.34 (0.61-3.00), 2.20 (0.96-5.06), and 2.69 (1.15-6.47) after adjusting for age, sex, cigarette smoking, alcohol intake, regular exercise, body mass index (BMI), mean arterial blood pressure, fasting plasma glucose, triglyceride, HDL-cholesterol, gamma-glutamyltransferase (GGT), and uric acid. CONCLUSION: These findings indicate that elevated WBC count is associated with arterial stiffness. Accordingly, early detection of an elevated WBC count is important for arterial function and the assessment of cardiovascular risk | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Ankle/blood supply | - |
dc.subject.MESH | Arteries/physiopathology* | - |
dc.subject.MESH | Biomechanical Phenomena | - |
dc.subject.MESH | Blood Pressure | - |
dc.subject.MESH | Brachial Artery | - |
dc.subject.MESH | Cardiovascular Diseases/physiopathology | - |
dc.subject.MESH | Electrocardiography | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Leukocyte Count* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Plethysmography | - |
dc.subject.MESH | Regression Analysis | - |
dc.title | Elevated white blood cell count is associated with arterial stiffness | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학) | - |
dc.contributor.googleauthor | Yong-Jae Lee | - |
dc.contributor.googleauthor | Ji-Won Lee | - |
dc.contributor.googleauthor | Jong-Koo Kim | - |
dc.contributor.googleauthor | Jung-Hyun Lee | - |
dc.contributor.googleauthor | Jin-Hyun Kim | - |
dc.contributor.googleauthor | Kil-Young Kwon | - |
dc.contributor.googleauthor | Hye-Ree Lee | - |
dc.contributor.googleauthor | Duk-Chul Lee | - |
dc.contributor.googleauthor | Jae-Yong Shim | - |
dc.identifier.doi | 10.1016/j.numecd.2008.02.003 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02982 | - |
dc.contributor.localId | A00210 | - |
dc.contributor.localId | A00915 | - |
dc.contributor.localId | A02207 | - |
dc.contributor.localId | A02716 | - |
dc.contributor.localId | A03126 | - |
dc.contributor.localId | A03203 | - |
dc.contributor.localId | A03310 | - |
dc.relation.journalcode | J02400 | - |
dc.identifier.eissn | 1590-3729 | - |
dc.identifier.pmid | 18456481 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0939475308000537 | - |
dc.subject.keyword | White blood cell | - |
dc.subject.keyword | Cardiovascular disease | - |
dc.subject.keyword | Arterial stiffness | - |
dc.subject.keyword | Pulse wave velocity | - |
dc.contributor.alternativeName | Lee, Yong Jae | - |
dc.contributor.alternativeName | Lee, Jung Hyun | - |
dc.contributor.alternativeName | Lee, Ji Won | - |
dc.contributor.alternativeName | Lee, Hye Ree | - |
dc.contributor.alternativeName | Kim, Jong Koo | - |
dc.contributor.alternativeName | Shim, Jae Yong | - |
dc.contributor.alternativeName | Lee, Duk Chul | - |
dc.contributor.affiliatedAuthor | Lee, Yong Jae | - |
dc.contributor.affiliatedAuthor | Kim, Jong Koo | - |
dc.contributor.affiliatedAuthor | Shim, Jae Yong | - |
dc.contributor.affiliatedAuthor | Lee, Duk Chul | - |
dc.contributor.affiliatedAuthor | Lee, Jung Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Ji Won | - |
dc.contributor.affiliatedAuthor | Lee, Hye Ree | - |
dc.citation.volume | 19 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 3 | - |
dc.citation.endPage | 7 | - |
dc.identifier.bibliographicCitation | NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, Vol.19(1) : 3-7, 2009 | - |
dc.identifier.rimsid | 36011 | - |
dc.type.rims | ART | - |
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