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아스피린 흡입 기관지 유발시험에서 후기 단독 양성 반응을 보인 아스피린 과민성 천식 1예

Other Titles
 A Case of Aspirin Intolerant Asthma Presenting Late Only Response during the Lysine-aspirin Bronchoprovocation Test 
 이은해  ;  이용원  ;  이재현  ;  박중원  ;  홍천수 
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기), Vol.30(4) : 329-332, 2010 
Journal Title
Journal of Asthma, Allergy and Clinical Immunology(천식 및 알레르기)
Issue Date
Asthma ; Aspirin ; Bronchoprovocation test
Aspirin and other non-steroidal anti-inflammatory agents (NSAIDs) cause bronchoconstriction in 10% to 20% of the adult asthmatic patients. The lysine-aspirin bronchial provocation test (L-ASA BPT) has become a widely used diagnostic test for detecting aspirin sensitivity in asthmatic patients. Several investigators have reported the development oflate and dual asthmatic responses as well as early asthmatic response. Most late asthmatic responses are known to occur within 4 to 6 hours of the L-ASA BPT. We report a case of aspirin-intolerant asthma with late only response during the L-ASA BPT. The late responses were notedtwice at 4 (greater than 20% decrease of FEV1) and 13 hours (greater than 30∼50% decrease of PFR with dyspnea) after the L-ASA BPT. In conclusion, we suggest that follow-up lung function monitoring will be needed for more than 12 hours after the L-ASA BPT to confirm delayed late asthmatic response. (Korean J Asthma Allergy Clin Immunol 2010;30:329-332)
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Lee, Yong Won(이용원)
Lee, Jae Hyun(이재현) ORCID logo https://orcid.org/0000-0002-0760-0071
Hong, Chein Soo(홍천수)
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